Title : Megestrol acetate reverses multidrug resistance and interacts with P-glycoprotein.

Pub. Date : 1992

PMID : 1348973






2 Functional Relationships(s)
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Protein Name
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1 At 100 microM, both steroids inhibited the binding of a Vinca alkaloid photoaffinity analog to P-glycoprotein (P-gp) in MDR human neuroblastic SH-SY5Y/VCR cells [which show greater than 1500-fold resistance to vincristine (VCR) in the tetrazolium dye (MTT) assay]. monooxyethylene trimethylolpropane tristearate ATP binding cassette subfamily B member 1 Homo sapiens
2 At 100 microM, both steroids inhibited the binding of a Vinca alkaloid photoaffinity analog to P-glycoprotein (P-gp) in MDR human neuroblastic SH-SY5Y/VCR cells [which show greater than 1500-fold resistance to vincristine (VCR) in the tetrazolium dye (MTT) assay]. monooxyethylene trimethylolpropane tristearate ATP binding cassette subfamily B member 1 Homo sapiens