Title : Inhibition of human ornithine decarboxylase activity by enantiomers of difluoromethylornithine.

Pub. Date : 2003 Oct 15

PMID : 12859253






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Purified human ODC-catalysed ornithine decarboxylation is highly stereospecific. Ornithine ornithine decarboxylase 1 Homo sapiens
2 D-DFMO was a more potent inhibitor (IC50 approximately 7.5 microM) when compared with D-ornithine (IC50 approximately 1.5 mM) of ODC-catalysed L-ornithine decarboxylation. Ornithine ornithine decarboxylase 1 Homo sapiens
3 D-DFMO was a more potent inhibitor (IC50 approximately 7.5 microM) when compared with D-ornithine (IC50 approximately 1.5 mM) of ODC-catalysed L-ornithine decarboxylation. Ornithine ornithine decarboxylase 1 Homo sapiens