Title : Identification of tetratricopeptide repeat 1 as an adaptor protein that interacts with heterotrimeric G proteins and the small GTPase Ras.

Pub. Date : 2003 Jun

PMID : 12748287






1 Functional Relationships(s)
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Protein Name
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1 TPR1 was found to compete with the Ras-binding domain (RBD) of Raf-1 for binding to the active Ras, suggesting that it may also compete with Ras GTPase-activating protein, thus contributing to the accumulation of GTP-bound Ras. Guanosine Triphosphate Raf-1 proto-oncogene, serine/threonine kinase Homo sapiens