PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12694072-2 2003 P-gp is encoded by the multiple drug resistance gene MDR1 and CYP3A is the major enzyme responsible for tacrolimus metabolism. Tacrolimus 104-114 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 62-67