Pub. Date : 2003 Jan
PMID : 12505937
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Volatile anesthetics did not attenuate the release of CGRP after spinal cord stimulation, whereas isoflurane at 2% and halothane at 1.5% significantly inhibited depressor responses to exogenously administered CGRP. | Halothane | calcitonin-related polypeptide alpha | Rattus norvegicus |
| 2 | Thus, isoflurane and halothane at large concentrations attenuate NANC depressor responses by attenuating the depressor action of CGRP, not CGRP release. | Halothane | calcitonin-related polypeptide alpha | Rattus norvegicus |
| 3 | IMPLICATIONS: The anesthetics isoflurane and halothane attenuate nonadrenergic, noncholinergic depressor responses mediated by calcitonin gene-related peptide in the rat without affecting the release of the peptide. | Halothane | calcitonin-related polypeptide alpha | Rattus norvegicus |