| Protein Name | calcitonin-related polypeptide alpha |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 24241 |
| Gene Symbol | Calca |
| UniProt | P01256 (CALCA_RAT), P01257 (CALC_RAT), A0A0G2JSX2 (A0A0G2JSX2_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
941
Total Number of Articles : 1836 |
Description |
calcitonin-related polypeptide alpha |
| Gene Summary |
Predicted to enable calcitonin receptor binding activity; hormone activity; and identical protein binding activity. Involved in several processes, including cellular response to nerve growth factor stimulus; cellular response to tumor necrosis factor; and vasodilation. Located in axon; extracellular space; and neuronal cell body. Is active in hippocampal mossy fiber to CA3 synapse and neuronal dense core vesicle. Used to study acute necrotizing pancreatitis; ischemia; and stomach disease. Biomarker of middle cerebral artery infarction; migraine; prediabetes syndrome; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in migraine and osteoporosis. Orthologous to human CALCA (calcitonin related polypeptide alpha). [provided by Alliance of Genome Resources, Jul 2025] |
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