Protein Name calcitonin-related polypeptide alpha
Organism Rattus norvegicus
Gene ID 24241
Gene Symbol

Calca

UniProt P01256 (CALCA_RAT), P01257 (CALC_RAT), A0A0G2JSX2 (A0A0G2JSX2_RAT)
Relationships Total Number of functionally related compound(s) : 941
Total Number of Articles : 1836
Description

calcitonin-related polypeptide alpha

Gene Summary

Predicted to enable calcitonin receptor binding activity and identical protein binding activity. Involved in several processes, including cellular response to nerve growth factor stimulus; cellular response to tumor necrosis factor; and vasodilation. Located in several cellular components, including axon; extracellular space; and neuronal cell body. Used to study acute necrotizing pancreatitis; ischemia; and stomach disease. Biomarker of prediabetes syndrome and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in migraine and osteoporosis. Orthologous to human CALCA (calcitonin related polypeptide alpha). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • calcitonin gene-related peptide 1
  • CGRP-I
  • alpha-type CGRP
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Properties