Pub. Date : 2002 Dec 15
PMID : 12488138
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We report here that a mixture of hypochlorous acid (HOCl) and nitrite (NO 2 - ) induces nitration, oxidation, and chlorination of tyrosine residues in human SP-A and inhibits SP-A"s ability to aggregate lipids and bind mannose. | Tyrosine | surfactant protein A1 | Homo sapiens |
| 2 | Moreover, both horseradish peroxidase and myeloperoxidase (MPO) can utilize NO 2 - and hydrogen peroxide (H 2 O 2 ) as substrates to catalyze tyrosine nitration in SP-A and inhibit its lipid aggregation function. | Tyrosine | surfactant protein A1 | Homo sapiens |