PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12488138-3 2002 We report here that a mixture of hypochlorous acid (HOCl) and nitrite (NO 2 - ) induces nitration, oxidation, and chlorination of tyrosine residues in human SP-A and inhibits SP-A"s ability to aggregate lipids and bind mannose. Tyrosine 130-138 surfactant protein A1 Homo sapiens 157-161 12488138-5 2002 Moreover, both horseradish peroxidase and myeloperoxidase (MPO) can utilize NO 2 - and hydrogen peroxide (H 2 O 2 ) as substrates to catalyze tyrosine nitration in SP-A and inhibit its lipid aggregation function. Tyrosine 142-150 surfactant protein A1 Homo sapiens 164-168