Pub. Date : 2002 Aug
PMID : 12154110
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Renal endothelin-1 participates in sodium and water handling, and its urinary excretion is increased in sodium-retentive states. | Sodium | endothelin 1 | Homo sapiens |
| 2 | Renal endothelin-1 participates in sodium and water handling, and its urinary excretion is increased in sodium-retentive states. | Sodium | endothelin 1 | Homo sapiens |
| 3 | In the renal cortex, low sodium diet caused a 194% increase in prepro-endothelin-1 mRNA (P<0.05), whereas endothelin-converting enzyme-1 type B and type A receptors remained unchanged. | Sodium | endothelin 1 | Homo sapiens |
| 4 | In conclusion, during low sodium diet, renal prepro-endothelin-1 synthesis increases mainly in the renal cortex (where no changes in receptors occur), whereas type B receptor is selectively enhanced in the renal medulla. | Sodium | endothelin 1 | Homo sapiens |