Title : Involvement of phospholipases D1 and D2 in sphingosine 1-phosphate-induced ERK (extracellular-signal-regulated kinase) activation and interleukin-8 secretion in human bronchial epithelial cells.

Pub. Date : 2002 Nov 1

PMID : 12149127






1 Functional Relationships(s)
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1 Treatment of Beas-2B cells with butan-1-ol, but not butan-3-ol, abrogated the S1P-induced phosphorylation of Raf-1 and ERK, suggesting that PLD is involved in this activation. Butanols glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens