Title : Structural basis for inhibition of cyclin-dependent kinase 9 by flavopiridol.

Pub. Date : 2002 Apr 26

PMID : 12054639






2 Functional Relationships(s)
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1 This structural model indicates that the inhibitor strongly binds to the ATP-binding pocket of CDK9 and the structural comparison of the complex CDK2-flavopiridol correlates the structural differences with differences in inhibition of these CDKs by flavopiridol. alvocidib cyclin dependent kinase 2 Homo sapiens
2 This structural model indicates that the inhibitor strongly binds to the ATP-binding pocket of CDK9 and the structural comparison of the complex CDK2-flavopiridol correlates the structural differences with differences in inhibition of these CDKs by flavopiridol. alvocidib cyclin dependent kinase 2 Homo sapiens