Title : Peroxisome proliferator-activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation.

Pub. Date : 2002 Apr

PMID : 11960303






1 Functional Relationships(s)
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1 In vivo treatment of SJL/J mice with PPARgamma agonists, 15-deoxydelta(12,14) prostaglandin J2 or Ciglitazone, decreased the duration and clinical severity of active immunization and adoptive transfer models of EAE. 9-deoxy-delta-9-prostaglandin D2 peroxisome proliferator activated receptor gamma Mus musculus