Title : Activation of extracellular signal-regulated kinase (ERK)1/2, but not p38 and c-Jun N-terminal kinase, is involved in signaling of a novel cytokine, ML-1.

Pub. Date : 2002 May 3

PMID : 11891214






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Selective MAP kinase kinase (MEK)1/2 inhibitors, PD98059 and U0126, inhibited, in a dose-dependent manner, ML-1-induced expression of IL-6 and IL-8. U 0126 interleukin 6 Homo sapiens