Title : Activation of the PKB/AKT pathway by ICAM-2.

Pub. Date : 2002 Jan

PMID : 11825565






1 Functional Relationships(s)
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Compound Name
Protein Name
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1 ICAM-2 induced tyrosine phosphorylation of ezrin and PI3K kinase membrane translocation, resulting in phosphatidylinositol 3,4,5 production, PDK-1 and AKT activation, and subsequent phosphorylation of AKT targets BAD, GSK3, and FKHR. Tyrosine intercellular adhesion molecule 2 Homo sapiens