| Protein Name | intercellular adhesion molecule 2 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 3384 |
| Gene Symbol | ICAM2 |
| UniProt | P13598 (ICAM2_HUMAN), Q6FHE2 (Q6FHE2_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
33
Total Number of Articles : 27 |
Description |
intercellular adhesion molecule 2 |
| Gene Summary |
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
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