Pub. Date : 2002 Jan
PMID : 11751610
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 11Beta-hydroxysteroid dehydrogenase 1 transforms 11-dehydrocorticosterone into transcriptionally active glucocorticoid in neonatal rat heart. | 11-dehydrocorticosterone | hydroxysteroid 11-beta dehydrogenase 1 | Rattus norvegicus |
| 2 | Enzyme activity studies demonstrated that 11betaHSD1 acted as a reductase only, converting biologically inactive 11-dehydrocorticosterone to corticosterone, which then stimulated serum and glucocorticoid-induced kinase gene transcription via GR. | 11-dehydrocorticosterone | hydroxysteroid 11-beta dehydrogenase 1 | Rattus norvegicus |