Title : Involvement of cholinergic and glutamatergic functions in working memory impairment induced by interleukin-1beta in rats.

Pub. Date : 2001 Nov 2

PMID : 11711044






1 Functional Relationships(s)
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1 The cholinesterase inhibitor physostigmine at a dose of 3.2 microg/side and D-cycloserine (1.0 and 10 microg/side), which is a partial agonist acting at the glycine binding site of the NMDA receptor/channel complex, reduced the increase in working memory errors induced by 100 ng/side interleukin-1beta. Physostigmine butyrylcholinesterase Rattus norvegicus