Protein Name butyrylcholinesterase
Organism Rattus norvegicus
Gene ID 65036
Gene Symbol

Bche

UniProt Q9JKC1 (Q9JKC1_RAT)
Relationships Total Number of functionally related compound(s) : 659
Total Number of Articles : 1060
Description

butyrylcholinesterase

Gene Summary

Enables choline binding activity and cholinesterase activity. Involved in several processes, including negative regulation of synaptic transmission; neuroblast differentiation; and response to folic acid. Located in endoplasmic reticulum lumen and extracellular space. Used to study amnestic disorder and hyperhomocysteinemia. Biomarker of leptospirosis and trypanosomiasis. Human ortholog(s) of this gene implicated in Alzheimer's disease; coronary artery disease (multiple); epilepsy; and inherited metabolic disorder (multiple). Orthologous to human BCHE (butyrylcholinesterase). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • cholinesterase
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Properties