Title : Differential involvement of caspases in hydroquinone-induced apoptosis in human leukemic hl-60 and jurkat cells.

Pub. Date : 2001 Sep 1

PMID : 11543641






1 Functional Relationships(s)
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1 In HL-60 cells, the general caspase inhibitor benzyloxycarbonyl-Val-Ala-Asp fluoromethyl ketone (Z-VAD.FMK) blocked activation of caspases-3/-7, cleavage of PARP, and DNA, but PS externalization and cytoplasmic changes were not significantly affected. Caspase Inhibitor VI poly(ADP-ribose) polymerase 1 Homo sapiens