Title : Functional and cellular interactions between nitric oxide and prostacyclin.

Pub. Date : 2001 Aug

PMID : 11489432






1 Functional Relationships(s)
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1 We suggest that NO, through cGMP-dependent protein kinases, produces the phosphorylation of a 104-kDa protein that is associated with inhibition in the activity of the COX-1, decreasing PGI(2) synthesis and thereby decreasing coronary PGI(2)-mediated vasodilatation. Epoprostenol prostaglandin-endoperoxide synthase 1 Homo sapiens