Title : The ability to accumulate deoxyuridine triphosphate and cellular response to thymidylate synthase (TS) inhibition.

Pub. Date : 2001 Aug 3

PMID : 11487279






1 Functional Relationships(s)
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1 Loss of viability following TS inhibition occurs as a consequence of depleted dTTP pools and at least in some cell lines, accumulation of dUTP and subsequent misincorporation of uracil into DNA. Uracil thymidylate synthetase Homo sapiens