Title : Differential regulation of 3beta-hydroxysteroid dehydrogenase type II and 17alpha-hydroxylase/lyase P450 in human adrenocortical carcinoma cells by epidermal growth factor and basic fibroblast growth factor.

Pub. Date : 2001 Jan

PMID : 11139773






1 Functional Relationships(s)
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1 Both the 3betaHSD II and CYP17 mRNAs were repressed by treatment with a calmodulin kinase II (CaMK II) inhibitor, KN-93, and were enhanced by a mitogen-activated protein kinase (MAPK) inhibitor, PD98059. KN 93 cytochrome P450 family 17 subfamily A member 1 Homo sapiens