Title : Stimulation of plasminogen activator and inhibitor in the lymphatic endothelium.

Pub. Date : 2000 Nov

PMID : 11078636






1 Functional Relationships(s)
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1 The effects of ECGF, histamine, and LPS on the presence of tPA and on enhancing the levels of mRNA reached maximum activity at 4 h and declined to levels below that of controls by 8 h. However, phorbol-treated cells exhibited reduced levels of tPA mRNA at 4 h, but was significantly increased by 8 h. A large-scale increase in PAI-1 mRNA steady-state levels was also stimulated by the agonists used in these studies. Histamine plasminogen activator, tissue type Homo sapiens