Title : Concordance between tumour cell activation by epidermal growth factor and alteration of cell sensitivity to cisplatin and lymphokine-activated killer cell activity.

Pub. Date : 2000 Jan-Feb

PMID : 10601618






2 Functional Relationships(s)
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1 Treatment of EGFr positive cell lines, Hep2, KB and MCF-7 but not EGFr negative Fen by EGF prior to exposure to cisplatin inhibited the cells by between 10-15% (p<0.05). Cisplatin epidermal growth factor receptor Homo sapiens
2 These data indicated that pre-exposure of tumour cells to EGF altered their response to cisplatin and LAK killing and this depended on the degree of EGFr expression. Cisplatin epidermal growth factor receptor Homo sapiens