Pub. Date : 1999 Aug 4
PMID : 10433621
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | METHODS: Using in situ hybridization, we analyzed RARbeta messenger RNA (mRNA) expression in bronchial biopsy specimens from heavy smokers, at baseline and after 6 months of treatment with 13-cis-retinoic acid (13-cis-RA) or placebo. | Isotretinoin | retinoic acid receptor beta | Homo sapiens |
2 | CONCLUSIONS: These results indicate that RARbeta is an independent marker of response to 13-cis-RA and may serve as an intermediate biomarker in chemoprevention trials of upper aerodigestive tract cancers. | Isotretinoin | retinoic acid receptor beta | Homo sapiens |