Title : Nuclear retinoid acid receptor beta in bronchial epithelium of smokers before and during chemoprevention.

Pub. Date : 1999 Aug 4

PMID : 10433621






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 METHODS: Using in situ hybridization, we analyzed RARbeta messenger RNA (mRNA) expression in bronchial biopsy specimens from heavy smokers, at baseline and after 6 months of treatment with 13-cis-retinoic acid (13-cis-RA) or placebo. Isotretinoin retinoic acid receptor beta Homo sapiens
2 CONCLUSIONS: These results indicate that RARbeta is an independent marker of response to 13-cis-RA and may serve as an intermediate biomarker in chemoprevention trials of upper aerodigestive tract cancers. Isotretinoin retinoic acid receptor beta Homo sapiens