Leucine

serpin family C member 1 ; Homo sapiens







11 Article(s)
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1 16940049 Disruption of a tight cluster surrounding tyrosine 131 in the native conformation of antithrombin III activates it for factor Xa inhibition. 2006 Oct 20 4
2 12939144 Introduction of a mutation in the shutter region of antithrombin (Phe77 --> Leu) increases affinity for heparin and decreases thermal stability. 2003 Sep 2 1
3 11159540 Cell-surface heparan sulfate proteoglycan-mediated regulation of human neutrophil migration by the serpin antithrombin III. 2001 Feb 15 1
4 11380262 The antithrombin P1 residue is important for target proteinase specificity but not for heparin activation of the serpin. Characterization of P1 antithrombin variants with altered proteinase specificity but normal heparin activation. 2001 Jun 5 1
5 7730349 Kinetic characterization of the proteinase binding defect in a reactive site variant of the serpin, antithrombin. Role of the P1' residue in transition-state stabilization of antithrombin-proteinase complex formation. 1995 Apr 28 2
6 7512382 Conformational change in antithrombin induced by heparin probed with a monoclonal antibody against the 1C/4B region. 1994 Apr 12 1
7 8037658 Interaction of heparin with synthetic antithrombin III peptide analogues. 1994 Jul 1 1
8 8392392 General features of the heparin-binding serpins antithrombin, heparin cofactor II and protein C inhibitor. 1993 Jun 1
9 8429008 Inhibition of dysthrombins Quick I and II by heparin cofactor II and antithrombin. 1993 Feb 15 1
10 3305015 Probing the heparin-binding domain of human antithrombin III with V8 protease. 1987 Sep 1 2
11 3080419 Antithrombin III Basel. Identification of a Pro-Leu substitution in a hereditary abnormal antithrombin with impaired heparin cofactor activity. 1986 Jan 25 1