Carbon

cytochrome P450 family 17 subfamily A member 1 ; Homo sapiens







17 Article(s)
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Pub. Year
#Total Relationships
1 33781841 Steroidogenic cytochrome P450 17A1 structure and function. 2021 May 15 2
2 34662099 Mechanism of the Clinically Relevant E305G Mutation in Human P450 CYP17A1. 2021 Nov 2 2
3 32007561 CYP17A1 exhibits 17αhydroxylase/17,20-lyase activity towards 11β-hydroxyprogesterone and 11-ketoprogesterone metabolites in the C11-oxy backdoor pathway. 2020 May 1
4 29283561 Human P450 CYP17A1: Control of Substrate Preference by Asparagine 202. 2018 Feb 6 2
5 29888793 Cytochrome b5 enhances androgen synthesis by rapidly reducing the CYP17A1 oxy-complex in the lyase step. 2018 Jul 2
6 24593890 [Congenital adrenal hyperplasia due to lack of 17α-hydroxylase: a report of a new mutation in the gene CYP17A1]. 2015 Jan 1
7 25224484 The post-translational regulation of 17,20 lyase activity. 2015 Jun 15 1
8 25482340 The diverse chemistry of cytochrome P450 17A1 (P450c17, CYP17A1). 2015 Jul 4
9 24584631 Carbon-carbon bond cleavage in activation of the prodrug nabumetone. 2014 May 2
10 24160919 Kinetic solvent isotope effect in human P450 CYP17A1-mediated androgen formation: evidence for a reactive peroxoanion intermediate. 2013 Nov 6 1
11 22064602 The 5α-androstanedione pathway to dihydrotestosterone in castration-resistant prostate cancer. 2012 Feb 1
12 21094255 A review of mechanistic studies on aromatase (CYP19) and 17α-hydroxylase-17,20-lyase (CYP17). 2011 May 5
13 15555906 The cationic charges on Arg347, Arg358 and Arg449 of human cytochrome P450c17 (CYP17) are essential for the enzyme's cytochrome b5-dependent acyl-carbon cleavage activities. 2004 Oct 5
14 12464252 The enantiomer of progesterone (ent-progesterone) is a competitive inhibitor of human cytochromes P450c17 and P450c21. 2003 Jan 1 1
15 12915666 The 17, 20-lyase activity of cytochrome p450c17 from human fetal testis favors the delta5 steroidogenic pathway. 2003 Aug 1
16 9365181 The impact of aromatase mechanism on other P450s. 1997 Apr 1
17 7578007 Mechanistic kinship between hydroxylation and desaturation reactions: acyl-carbon bond cleavage promoted by pig and human CYP17 (P-450(17)alpha; 17 alpha-hydroxylase-17,20-lyase). 1995 Oct 31 1