Reactive Oxygen Species

phosphatase and tensin homolog ; Homo sapiens







57 Article(s)
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Pub. Year
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1 33442914 The interplay of ROS and the PI3K/Akt pathway in autophagy regulation. 2022 Feb 1
2 35143421 SENP7 senses oxidative stress to sustain metabolic fitness and antitumor functions of CD8+ T cells. 2022 Apr 1 6
3 35217209 Leonurus japonicus Houttuyn induces reactive oxygen species-mediated apoptosis via regulation of miR-19a-3p/PTEN/PI3K/AKT in U937 and THP-1 cells. 2022 Jun 12 1
4 33249138 The critical role of redox regulation of PTEN and peroxiredoxin III in alcoholic fatty liver. 2021 Jan 1
5 34091997 AQP3-mediated H2 O2 uptake inhibits LUAD autophagy by inactivating PTEN. 2021 Aug 1
6 34632072 Aberrant expression of PI3K/AKT signaling is involved in apoptosis resistance of hepatocellular carcinoma. 2021 2
7 32141453 Self-responsive co-delivery system for remodeling tumor intracellular microenvironment to promote PTEN-mediated anti-tumor therapy. 2020 May 7 3
8 32413744 Redox regulation of tumor suppressor PTEN in cell signaling. 2020 Jul 2
9 33553145 Both Hypoxia-Inducible Factor 1 and MAPK Signaling Pathway Attenuate PI3K/AKT via Suppression of Reactive Oxygen Species in Human Pluripotent Stem Cells. 2020 1
10 30816513 Resveratrol induces cell death through ROS‑dependent downregulation of Notch1/PTEN/Akt signaling in ovarian cancer cells. 2019 Apr 1
11 31053167 ROS play an important role in ATPR inducing differentiation and inhibiting proliferation of leukemia cells by regulating the PTEN/PI3K/AKT signaling pathway. 2019 May 3 4
12 31210839 Bloom Syndrome Protein Activates AKT and PRAS40 in Prostate Cancer Cells. 2019 1
13 29274354 Ochratoxin A exposure decreased sperm motility via the AMPK and PTEN signaling pathways. 2018 Feb 1 1
14 29723979 Reactive Oxygen Species, Superoxide Dimutases, and PTEN-p53-AKT-MDM2 Signaling Loop Network in Mesenchymal Stem/Stromal Cells Regulation. 2018 May 1 1
15 30042494 Mitochondrial ROS-derived PTEN oxidation activates PI3K pathway for mTOR-induced myogenic autophagy. 2018 Nov 1
16 30595797 NQO1 Is Regulated by PTEN in Glioblastoma, Mediating Cell Proliferation and Oxidative Stress. 2018 3
17 26892626 Clearance of Damaged Mitochondria Through PINK1 Stabilization by JNK and ERK MAPK Signaling in Chlorpyrifos-Treated Neuroblastoma Cells. 2017 Apr 2
18 28557373 PTEN inhibits replicative senescence-induced MMP-1 expression by regulating NOX4-mediated ROS in human dermal fibroblasts. 2017 Nov 2
19 29085372 miR-148a-3p Mediates Notch Signaling to Promote the Differentiation and M1 Activation of Macrophages. 2017 1
20 26797275 Identification of novel cell survival regulation in diabetic embryopathy via phospholipidomic profiling. 2016 Feb 12 1
21 27210502 PTEN-regulated AKT/FoxO3a/Bim signaling contributes to Human cell glioblastoma apoptosis by platinum-maurocalcin conjugate. 2016 Aug 1
22 27367846 Hypo-CpG methylation controls PTEN expression and cell apoptosis in irradiated lung. 2016 Aug 4
23 28003865 Skin Aging-Dependent Activation of the PI3K Signaling Pathway via Downregulation of PTEN Increases Intracellular ROS in Human Dermal Fibroblasts. 2016 2
24 25158671 The effects of high glucose levels on reactive oxygen species-induced apoptosis and involved signaling in human vascular endothelial cells. 2015 Apr 1
25 25352295 PI3K/AKT/PTEN pathway as a target for Crohn's disease therapy (Review). 2015 Jan 1
26 25388655 Hepatitis C virus NS5A drives a PTEN-PI3K/Akt feedback loop to support cell survival. 2015 Jun 5
27 25579427 Myeloid cell-derived reactive oxygen species externally regulate the proliferation of myeloid progenitors in emergency granulopoiesis. 2015 Jan 20 1
28 25870146 Mechanistic Rationale to Target PTEN-Deficient Tumor Cells with Inhibitors of the DNA Damage Response Kinase ATM. 2015 Jun 1 1
29 25965299 Redox signalling to nuclear regulatory proteins by reactive oxygen species contributes to oestrogen-induced growth of breast cancer cells. 2015 May 12 1
30 26418532 Redox Modulation of PTEN Phosphatase Activity by Hydrogen Peroxide and Bisperoxidovanadium Complexes. 2015 Nov 9 1
31 24052409 Mahanine synergistically enhances cytotoxicity of 5-fluorouracil through ROS-mediated activation of PTEN and p53/p73 in colon carcinoma. 2014 Jan 3
32 24063548 PTEN phosphorylation and nuclear export mediate free fatty acid-induced oxidative stress. 2014 Mar 20 2
33 24494199 Intracellular redox status controls membrane localization of pro- and anti-migratory signaling molecules. 2014 1
34 25504433 Acidosis promotes invasiveness of breast cancer cells through ROS-AKT-NF-κB pathway. 2014 Dec 15 1
35 23313933 Redox regulation of tumor suppressor PTEN in cancer and aging (Review). 2013 Mar 3
36 23315288 ROS-mediated activation of AKT induces apoptosis via pVHL in prostate cancer cells. 2013 Apr 1
37 23392169 PTEN-regulated AKT/FoxO3a/Bim signaling contributes to reactive oxygen species-mediated apoptosis in selenite-treated colorectal cancer cells. 2013 Feb 7 2
38 23832602 Reactive oxygen species-dependent down-regulation of tumor suppressor genes PTEN, USP28, DRAM, TIGAR, and CYLD under oxidative stress. 2013 Dec 1
39 23867870 Antioxidant properties of mesalamine in colitis inhibit phosphoinositide 3-kinase signaling in progenitor cells. 2013 Sep 1
40 24101387 The effect of reactive oxygen species on the synthesis of prostanoids from arachidonic acid. 2013 Aug 1
41 22335598 Ligand-activated PPARδ inhibits UVB-induced senescence of human keratinocytes via PTEN-mediated inhibition of superoxide production. 2012 May 15 1
42 22940494 Redox control of cytosolic Akt phosphorylation in PTEN null cells. 2012 Nov 1 1
43 20926450 Naturally occurring germline and tumor-associated mutations within the ATP-binding motifs of PTEN lead to oxidative damage of DNA associated with decreased nuclear p53. 2011 Jan 1 1
44 21072054 PTEN status switches cell fate between premature senescence and apoptosis in glioma exposed to ionizing radiation. 2011 Apr 3
45 21195169 Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death. 2011 Mar 1 1
46 21345072 The protective effect of Cu/Zn-SOD against oxidative stress after PTEN deletion. 2011 May 1
47 21627959 ROS enhances CXCR4-mediated functions through inactivation of PTEN in prostate cancer cells. 2011 Jul 1 6
48 21951851 Mitochondrial ROS generation for regulation of autophagic pathways in cancer. 2011 Oct 14 1
49 20937881 Methionine sulfoxide reductase A down-regulation in human breast cancer cells results in a more aggressive phenotype. 2010 Oct 26 1
50 19824470 [Reactive oxygen species in regulation of cell migration. The role of thioredoxin reductase]. 2009 1