Serine

mitogen-activated protein kinase kinase kinase 8 ; Homo sapiens







13 Article(s)
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1 35051238 Influenza-induced Tpl2 expression within alveolar epithelial cells is dispensable for host viral control and anti-viral immunity. 2022 2
2 33361430 Foot-and-Mouth Disease Virus Structural Protein VP1 Destroys the Stability of TPL2 Trimer by Degradation TPL2 to Evade Host Antiviral Immunity. 2020 Dec 23 2
3 30853309 Advancement in TPL2-regulated innate immune response. 2019 May 3
4 31498175 Pathologic Characteristics of Spitz Melanoma With MAP3K8 Fusion or Truncation in a Pediatric Cohort. 2019 Dec 1
5 24912162 IκB kinase-induced interaction of TPL-2 kinase with 14-3-3 is essential for Toll-like receptor activation of ERK-1 and -2 MAP kinases. 2014 Jun 10 6
6 22988300 IκB kinase 2 regulates TPL-2 activation of extracellular signal-regulated kinases 1 and 2 by direct phosphorylation of TPL-2 serine 400. 2012 Nov 6
7 21182083 Cystatin cures visceral leishmaniasis by NF-κB-mediated proinflammatory response through co-ordination of TLR/MyD88 signaling with p105-Tpl2-ERK pathway. 2011 Jan 1
8 19808894 Tpl2 kinase is upregulated in adipose tissue in obesity and may mediate interleukin-1beta and tumor necrosis factor-{alpha} effects on extracellular signal-regulated kinase activation and lipolysis. 2010 Jan 1
9 17724252 Cot, a novel kinase of histone H3, induces cellular transformation through up-regulation of c-fos transcriptional activity. 2008 Jan 5
10 18439422 NIK and Cot cooperate to trigger NF-kappaB p65 phosphorylation. 2008 Jun 27 1
11 17709378 Phosphorylation of TPL-2 on serine 400 is essential for lipopolysaccharide activation of extracellular signal-regulated kinase in macrophages. 2007 Nov 2
12 15128824 Transient and selective NF-kappa B p65 serine 536 phosphorylation induced by T cell costimulation is mediated by I kappa B kinase beta and controls the kinetics of p65 nuclear import. 2004 May 15 2
13 12138205 Akt-dependent phosphorylation specifically regulates Cot induction of NF-kappa B-dependent transcription. 2002 Aug 1