Title : Tpl2 kinase is upregulated in adipose tissue in obesity and may mediate interleukin-1beta and tumor necrosis factor-{alpha} effects on extracellular signal-regulated kinase activation and lipolysis.

Pub. Date : 2010 Jan

PMID : 19808894






1 Functional Relationships(s)
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1 Importantly, Tpl2 was implicated in cytokine-induced lipolysis and in insulin receptor substrate-1 serine phosphorylation. Serine mitogen-activated protein kinase kinase kinase 8 Homo sapiens