| 1 |
35221331 | Phosphorylated NFS1 weakens oxaliplatin-based chemosensitivity of colorectal cancer by preventing PANoptosis. | 2022 Feb 28 |
1 |
| 2 |
35377584 | Structural diversity of cysteine desulfurases involved in iron-sulfur cluster biosynthesis. | 2022 |
1 |
| 3 |
33457206 | A recurring NFS1 pathogenic variant causes a mitochondrial disorder with variable intra-familial patient outcomes. | 2021 Mar |
1 |
| 4 |
34452919 | Genome-wide synthetic lethal screen unveils novel CAIX-NFS1/xCT axis as a targetable vulnerability in hypoxic solid tumors. | 2021 Aug |
1 |
| 5 |
34612205 | Divergent acyl carrier protein decouples mitochondrial Fe-S cluster biogenesis from fatty acid synthesis in malaria parasites. | 2021 Oct 6 |
1 |
| 6 |
32131593 | Molecular Mechanism of ISC Iron-Sulfur Cluster Biogenesis Revealed by High-Resolution Native Mass Spectrometry. | 2020 Apr 1 |
1 |
| 7 |
32202031 | Distribution of Nitrogen-Fixation Genes in Prokaryotes Containing Alternative Nitrogenases. | 2020 Jun 15 |
1 |
| 8 |
30975898 | Mechanism of frataxin "bypass" in human iron-sulfur cluster biosynthesis with implications for Friedreich's ataxia. | 2019 Jun 7 |
1 |
| 9 |
31101807 | Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism. | 2019 May 17 |
1 |
| 10 |
31395877 | Physiologically relevant reconstitution of iron-sulfur cluster biosynthesis uncovers persulfide-processing functions of ferredoxin-2 and frataxin. | 2019 Aug 8 |
3 |
| 11 |
31511419 | Mechanism of activation of the human cysteine desulfurase complex by frataxin. | 2019 Sep 24 |
1 |
| 12 |
29309586 | Cytosolic HSC20 integrates de novo iron-sulfur cluster biogenesis with the CIAO1-mediated transfer to recipients. | 2018 Mar 1 |
3 |
| 13 |
29596470 | Dysfunction in the mitochondrial Fe-S assembly machinery leads to formation of the chemoresistant truncated VDAC1 isoform without HIF-1α activation. | 2018 |
1 |
| 14 |
29782976 | LdIscU is a [2Fe-2S] scaffold protein which interacts with LdIscS and its expression is modulated by Fe-S proteins in Leishmania donovani. | 2018 Sep |
1 |
| 15 |
30031876 | Zinc(II) binding on human wild-type ISCU and Met140 variants modulates NFS1 desulfurase activity. | 2018 Sep |
2 |
| 16 |
28271877 | The N-Terminus of Iron-Sulfur Cluster Assembly Factor ISD11 Is Crucial for Subcellular Targeting and Interaction with l-Cysteine Desulfurase NFS1. | 2017 Mar 28 |
2 |
| 17 |
28323419 | The Role of SufS Is Restricted to Fe-S Cluster Biosynthesis in Escherichia coli. | 2017 Apr 11 |
3 |
| 18 |
28548666 | Zinc and the iron donor frataxin regulate oligomerization of the scaffold protein to form new Fe-S cluster assembly centers. | 2017 Jun 21 |
1 |
| 19 |
28634302 | Structure of human Fe-S assembly subcomplex reveals unexpected cysteine desulfurase architecture and acyl-ACP-ISD11 interactions. | 2017 Jul 3 |
2 |
| 20 |
28766335 | Functional Complementation Studies Reveal Different Interaction Partners of Escherichia coli IscS and Human NFS1. | 2017 Aug 29 |
3 |
| 21 |
28882199 | Defining the Architecture of the Core Machinery for the Assembly of Fe-S Clusters in Human Mitochondria. | 2017 |
2 |
| 22 |
29168506 | NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis. | 2017 Nov 30 |
2 |
| 23 |
26842892 | Protection of scaffold protein Isu from degradation by the Lon protease Pim1 as a component of Fe-S cluster biogenesis regulation. | 2016 Apr 1 |
1 |
| 24 |
26941001 | Architecture of the Yeast Mitochondrial Iron-Sulfur Cluster Assembly Machinery: THE SUB-COMPLEX FORMED BY THE IRON DONOR, Yfh1 PROTEIN, AND THE SCAFFOLD, Isu1 PROTEIN. | 2016 May 6 |
2 |
| 25 |
27427956 | The Eukaryotic-Specific ISD11 Is a Complex-Orphan Protein with Ability to Bind the Prokaryotic IscS. | 2016 |
1 |
| 26 |
27519411 | Architecture of the Human Mitochondrial Iron-Sulfur Cluster Assembly Machinery. | 2016 Sep 30 |
2 |
| 27 |
27653419 | Real-Time Kinetic Probes Support Monothiol Glutaredoxins As Intermediate Carriers in Fe-S Cluster Biosynthetic Pathways. | 2016 Nov 18 |
1 |
| 28 |
25398879 | Fe-S cluster biogenesis in isolated mammalian mitochondria: coordinated use of persulfide sulfur and iron and requirements for GTP, NADH, and ATP. | 2015 Jan 2 |
6 |
| 29 |
25597503 | Mammalian frataxin directly enhances sulfur transfer of NFS1 persulfide to both ISCU and free thiols. | 2015 Jan 19 |
2 |
| 30 |
25688831 | Ferredoxin, in conjunction with NADPH and ferredoxin-NADP reductase, transfers electrons to the IscS/IscU complex to promote iron-sulfur cluster assembly. | 2015 Sep |
1 |
| 31 |
26016389 | The Human Iron-Sulfur Assembly Complex Catalyzes the Synthesis of [2Fe-2S] Clusters on ISCU2 That Can Be Transferred to Acceptor Molecules. | 2015 Jun 30 |
1 |
| 32 |
26016518 | Frataxin Accelerates [2Fe-2S] Cluster Formation on the Human Fe-S Assembly Complex. | 2015 Jun 30 |
3 |
| 33 |
26032732 | Interaction of frataxin, an iron binding protein, with IscU of Fe-S clusters biogenesis pathway and its upregulation in AmpB resistant Leishmania donovani. | 2015 Aug |
1 |
| 34 |
26342079 | Mapping Key Residues of ISD11 Critical for NFS1-ISD11 Subcomplex Stability: IMPLICATIONS IN THE DEVELOPMENT OF MITOCHONDRIAL DISORDER, COXPD19. | 2015 Oct 23 |
3 |
| 35 |
24498631 | Exome sequencing identifies NFS1 deficiency in a novel Fe-S cluster disease, infantile mitochondrial complex II/III deficiency. | 2014 Jan |
2 |
| 36 |
24573684 | The presence of multiple cellular defects associated with a novel G50E iron-sulfur cluster scaffold protein (ISCU) mutation leads to development of mitochondrial myopathy. | 2014 Apr 11 |
1 |
| 37 |
24971490 | Human frataxin activates Fe-S cluster biosynthesis by facilitating sulfur transfer chemistry. | 2014 Aug 5 |
4 |
| 38 |
25044349 | The scaffold protein IscU retains a structured conformation in the Fe-S cluster assembly complex. | 2014 Jul 21 |
1 |
| 39 |
25062827 | Reactive oxygen species regulates expression of iron-sulfur cluster assembly protein IscS of Leishmania donovani. | 2014 Oct |
3 |
| 40 |
23265191 | Mammalian frataxin controls sulfur production and iron entry during de novo Fe4S4 cluster assembly. | 2013 Jan 16 |
2 |
| 41 |
23593335 | The L-cysteine desulfurase NFS1 is localized in the cytosol where it provides the sulfur for molybdenum cofactor biosynthesis in humans. | 2013 |
1 |
| 42 |
23946486 | Binding of the chaperone Jac1 protein and cysteine desulfurase Nfs1 to the iron-sulfur cluster scaffold Isu protein is mutually exclusive. | 2013 Oct 4 |
1 |
| 43 |
24045011 | The effect of the adaptor protein Isd11 on the quaternary structure of the eukaryotic cysteine desulphurase Nfs1. | 2013 Oct 18 |
1 |
| 44 |
22294093 | Competing pathways control host resistance to virus via tRNA modification and programmed ribosomal frameshifting. | 2012 Jan 31 |
1 |
| 45 |
22352884 | Effector role reversal during evolution: the case of frataxin in Fe-S cluster biosynthesis. | 2012 Mar 27 |
2 |
| 46 |
22689995 | Cysteine desulfurase Nfs1 and Pim1 protease control levels of Isu, the Fe-S cluster biogenesis scaffold. | 2012 Jun 26 |
1 |
| 47 |
20957368 | Expression, purification, and characterization of an iron chaperon protein CyaY from Acidithiobacillus ferrooxidans. | 2011 Mar |
2 |
| 48 |
21298097 | Mammalian frataxin: an essential function for cellular viability through an interaction with a preformed ISCU/NFS1/ISD11 iron-sulfur assembly complex. | 2011 Jan 26 |
1 |
| 49 |
21671584 | Friedreich's ataxia variants I154F and W155R diminish frataxin-based activation of the iron-sulfur cluster assembly complex. | 2011 Jul 26 |
1 |
| 50 |
21926174 | Leucine biosynthesis regulates cytoplasmic iron-sulfur enzyme biogenesis in an Atm1p-independent manner. | 2011 Nov 25 |
1 |