Title : Functional Complementation Studies Reveal Different Interaction Partners of Escherichia coli IscS and Human NFS1.

Pub. Date : 2017 Aug 29

PMID : 28766335






3 Functional Relationships(s)
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1 While E. coli IscS has a versatile role in the cell and was shown to have numerous interaction partners, NFS1 is mainly localized in mitochondria with a crucial role in the biosynthesis of Fe-S clusters. Iron NFS1 cysteine desulfurase Homo sapiens
2 Our results show that human NFS1 and E. coli IscS share conserved binding sites for proteins involved in Fe-S cluster assembly like IscU, but not with proteins for tRNA thio modifications or Moco biosynthesis. Iron NFS1 cysteine desulfurase Homo sapiens
3 Our results show that human NFS1 and E. coli IscS share conserved binding sites for proteins involved in Fe-S cluster assembly like IscU, but not with proteins for tRNA thio modifications or Moco biosynthesis. Iron NFS1 cysteine desulfurase Homo sapiens