calcein AM

ATP binding cassette subfamily B member 1 ; Homo sapiens







78 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35162941 The Ubiquitin E3 Ligase Nedd4 Regulates the Expression and Amyloid-β Peptide Export Activity of P-Glycoprotein. 2022 Jan 18 1
2 35327403 Infigratinib (BGJ 398), a Pan-FGFR Inhibitor, Targets P-Glycoprotein and Increases Chemotherapeutic-Induced Mortality of Multidrug-Resistant Tumor Cells. 2022 Mar 3 2
3 33735724 A novel flavonoid from Fissistigma cupreonitens, 5‑hydroxy‑7,8‑dimethoxyflavanone, competitively inhibited the efflux function of human P-glycoprotein and reversed cancer multi-drug resistance. 2021 May 1
4 30353640 Determination of Reference Values of MDR-ABC Transporter Activities in CD3+ Lymphocytes of Healthy Volunteers Using a Flow Cytometry Based Method. 2019 Nov 2
5 30594677 Novel chalcone and flavone derivatives as selective and dual inhibitors of the transport proteins ABCB1 and ABCG2. 2019 Feb 15 1
6 30925062 Identification of Thienopyrimidine Scaffold as an Inhibitor of the ABC Transport Protein ABCC1 (MRP1) and Related Transporters Using a Combined Virtual Screening Approach. 2019 May 9 1
7 31538529 3-benzazecine-based cyclic allene derivatives as highly potent P-glycoprotein inhibitors overcoming doxorubicin multidrug resistance. 2019 Aug 1
8 31581572 Development of a Novel Quinoline Derivative as a P-Glycoprotein Inhibitor to Reverse Multidrug Resistance in Cancer Cells. 2019 Oct 1 1
9 31639417 Reversible inhibition of efflux transporters by hydrogel microdevices. 2019 Dec 1
10 30023810 Effects of Natural Polyphenols on the Expression of Drug Efflux Transporter P-Glycoprotein in Human Intestinal Cells. 2018 Feb 28 1
11 30051196 Screening of Drug-Transporter Interactions in a 3D Microfluidic Renal Proximal Tubule on a Chip. 2018 Jul 26 1
12 30469543 Taxifolin Resensitizes Multidrug Resistance Cancer Cells via Uncompetitive Inhibition of P-Glycoprotein Function. 2018 Nov 22 2
13 28712845 Dual inhibitors of the human blood-brain barrier drug efflux transporters P-glycoprotein and ABCG2 based on the antiviral azidothymidine. 2017 Oct 1 1
14 28912036 Dual effects of the PI3K inhibitor ZSTK474 on multidrug efflux pumps in resistant cancer cells. 2017 Nov 15 1
15 29016119 9-Deazapurines as Broad-Spectrum Inhibitors of the ABC Transport Proteins P-Glycoprotein, Multidrug Resistance-Associated Protein 1, and Breast Cancer Resistance Protein. 2017 Nov 9 1
16 26797828 A Potent and Selective P-gp Modulator for Altering Multidrug Resistance Due to Pump Overexpression. 2016 Feb 17 2
17 26887049 Substrate-specific effects of pirinixic acid derivatives on ABCB1-mediated drug transport. 2016 Mar 8 1
18 27216424 Screening dietary flavonoids for the reversal of P-glycoprotein-mediated multidrug resistance in cancer. 2016 Jul 19 1
19 30475507 Substrate Specificity of Aglaia loheri Active Isolate towards P-glycoprotein in Multidrug-Resistant Cancer Cells. 2016 Nov 1
20 25265513 Reversal of human multi-drug resistance leukaemic cells by stemofoline derivatives via inhibition of P-glycoprotein function. 2015 May 1
21 25802484 ABCB1 transporter and Toll-like receptor 4 in trabecular meshwork cells. 2015 1
22 25907295 Itraconazole and clarithromycin inhibit P-glycoprotein activity in primary human sinonasal epithelial cells. 2015 Jun 1
23 25976226 Evaluation of dual P-gp-BCRP inhibitors as nanoparticle formulation. 2015 Sep 18 1
24 26012726 Arylamino Esters As P-Glycoprotein Modulators: SAR Studies to Establish Requirements for Potency and Selectivity. 2015 Aug 1
25 26287374 P-Glycoprotein Induction Ameliorates Colistin Induced Nephrotoxicity in Cultured Human Proximal Tubular Cells. 2015 1
26 24521085 Mucoadhesive properties and interaction with P-glycoprotein (P-gp) of thiolated-chitosans and -glycol chitosans and corresponding parent polymers: a comparative study. 2014 Mar 10 1
27 24641346 Multilayer spheroids to quantify drug uptake and diffusion in 3D. 2014 Jul 7 2
28 24907976 Ferrocene and (arene)ruthenium(II) complexes of the natural anticancer naphthoquinone plumbagin with enhanced efficacy against resistant cancer cells and a genuine mode of action. 2014 Sep 2
29 24949819 Development and validation of a LC-MS/MS method for assessment of an anti-inflammatory indolinone derivative by in vitro blood-brain barrier models. 2014 Sep 2
30 24954033 Resistance to daunorubicin, imatinib, or nilotinib depends on expression levels of ABCB1 and ABCG2 in human leukemia cells. 2014 Aug 5 1
31 25192198 Overexpression of human ABCB1 in cancer cells leads to reduced activity of GSK461364, a specific inhibitor of polo-like kinase 1. 2014 Oct 6 1
32 23278697 Phyllanthin and hypophyllanthin inhibit function of P-gp but not MRP2 in Caco-2 cells. 2013 Feb 1
33 23593196 Screening compounds with a novel high-throughput ABCB1-mediated efflux assay identifies drugs with known therapeutic targets at risk for multidrug resistance interference. 2013 2
34 23731729 The drug efflux pump Pgp1 in pro-inflammatory lymphocytes is a target for novel treatment strategies in COPD. 2013 Jun 3 1
35 23994641 Physicochemical characterization and in vitro permeation of an indirubin derivative. 2013 Nov 20 2
36 24058883 Cannabidiol changes P-gp and BCRP expression in trophoblast cell lines. 2013 2
37 24098380 Specific increase in MDR1 mediated drug-efflux in human brain endothelial cells following co-exposure to HIV-1 and saquinavir. 2013 1
38 24900683 Benzanilide-Biphenyl Replacement: A Bioisosteric Approach to Quinoline Carboxamide-Type ABCG2 Modulators. 2013 Apr 11 1
39 22079615 Protective effect of methylprednisolone on paraquat-induced A549 cell cytotoxicity via induction of efflux transporter, P-glycoprotein expression. 2012 Jan 25 1
40 22112540 Investigation of chalcones and benzochalcones as inhibitors of breast cancer resistance protein. 2012 Jan 1 2
41 22353810 Detection and characterisation of multi-drug resistance protein 1 (MRP-1) in human mitochondria. 2012 Mar 13 1
42 22727780 Thiorhodamines containing amide and thioamide functionality as inhibitors of the ATP-binding cassette drug transporter P-glycoprotein (ABCB1). 2012 Jul 15 2
43 23037162 Effects of Kampo medicines on MDR-1-mediated multidrug resistance in human hepatocellular carcinoma HuH-7/PTX cells. 2012 5
44 20676745 YC-1, a novel potential anticancer agent, inhibit multidrug-resistant protein via cGMP-dependent pathway. 2011 Dec 1
45 21239442 Corticosteroid regulation of P-glycoprotein in the developing blood-brain barrier. 2011 Mar 1
46 21570282 Solid phase synthesis of tariquidar-related modulators of ABC transporters preferring breast cancer resistance protein (ABCG2). 2011 Jun 15 1
47 24309308 Role of p-glycoprotein expression and function in cystinotic renal proximal tubular cells. 2011 Oct 27 3
48 19285492 Glucosylceramide synthase inhibitors sensitise CLL cells to cytotoxic agents without reversing P-gp functional activity. 2009 May 1 3
49 19721237 P-glycoprotein mediates efflux transport of darunavir in human intestinal Caco-2 and ABCB1 gene-transfected renal LLC-PK1 cell lines. 2009 Sep 2
50 19739602 Evaluation of the flavonoid oroxylin A as an inhibitor of P-glycoprotein-mediated cellular efflux. 2009 Sep 1