Title : Phyllanthin and hypophyllanthin inhibit function of P-gp but not MRP2 in Caco-2 cells.

Pub. Date : 2013 Feb

PMID : 23278697






1 Functional Relationships(s)
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1 METHODS: The activity of P-gp and MRP2 was determined in the uptake assays by monitoring the intracellular accumulation of their specific substrates (calcein acetoxymethyl ester and 5(6)-carboxy-2",7"-dichlorofluorescein diacetate, respectively) with fluorescence spectroscopy. calcein AM ATP binding cassette subfamily B member 1 Homo sapiens