| 1 |
35215354 | Evaluation of the Potency of Anti-HIV and Anti-HCV Drugs to Inhibit P-Glycoprotein Mediated Efflux of Digoxin in Caco-2 Cell Line and Human Precision-Cut Intestinal Slices. | 2022 Feb 18 |
1 |
| 2 |
35350768 | The Resistance of Cancer Cells to Palbociclib, a Cyclin-Dependent Kinase 4/6 Inhibitor, is Mediated by the ABCB1 Transporter. | 2022 |
3 |
| 3 |
34977876 | Overcoming multidrug resistance by knockout of ABCB1 gene using CRISPR/Cas9 system in SW620/Ad300 colorectal cancer cells. | 2021 Dec |
1 |
| 4 |
31106148 | Glesatinib, a c-MET/SMO Dual Inhibitor, Antagonizes P-glycoprotein Mediated Multidrug Resistance in Cancer Cells. | 2019 |
1 |
| 5 |
30135242 | Application of Intestinal Epithelial Cells Differentiated from Human Induced Pluripotent Stem Cells for Studies of Prodrug Hydrolysis and Drug Absorption in the Small Intestine. | 2018 Nov |
2 |
| 6 |
28031414 | Inhibition of the Human ABC Efflux Transporters P-gp and BCRP by the BDE-47 Hydroxylated Metabolite 6-OH-BDE-47: Considerations for Human Exposure. | 2017 Jan |
2 |
| 7 |
26296969 | Semi-synthetic ocotillol analogues as selective ABCB1-mediated drug resistance reversal agents. | 2015 Sep 15 |
1 |
| 8 |
25985578 | Modulation of P-glycoprotein function and multidrug resistance in cancer cells by Thai plant extracts. | 2014 Nov |
1 |
| 9 |
23673445 | PD173074, a selective FGFR inhibitor, reverses ABCB1-mediated drug resistance in cancer cells. | 2013 Jul |
1 |
| 10 |
19631272 | Xenopus laevis oocytes expressing human P-glycoprotein: probing trans- and cis-inhibitory effects on [3H]vinblastine and [3H]digoxin efflux. | 2010 Jan |
2 |
| 11 |
20080907 | Tacrolimus, a calcineurin inhibitor, overcomes treatment unresponsiveness mediated by P-glycoprotein on lymphocytes in refractory rheumatoid arthritis. | 2010 Mar |
1 |
| 12 |
19414624 | Up-regulation of transporters and enzymes by the vitamin D receptor ligands, 1alpha,25-dihydroxyvitamin D3 and vitamin D analogs, in the Caco-2 cell monolayer. | 2009 Aug |
1 |
| 13 |
19918100 | P-glycoprotein, multidrug resistance-associated proteins and human organic anion transporting polypeptide influence the intracellular accumulation of atazanavir. | 2009 |
1 |
| 14 |
18668443 | Validation and application of Caco-2 assays for the in vitro evaluation of development candidate drugs as substrates or inhibitors of P-glycoprotein to support regulatory submissions. | 2008 Jul |
1 |
| 15 |
18762730 | Reversal effects of Ca2+ antagonists on multidrug resistance via down-regulation of MDR1 mRNA. | 2008 Feb 8 |
3 |
| 16 |
16299163 | Demonstration of docosahexaenoic acid as a bioavailability enhancer for CYP3A substrates: in vitro and in vivo evidence using cyclosporin in rats. | 2006 Feb |
1 |
| 17 |
16388406 | Effects of acid and lactone forms of eight HMG-CoA reductase inhibitors on CYP-mediated metabolism and MDR1-mediated transport. | 2006 Mar |
1 |
| 18 |
15875185 | Potent reversal of multidrug resistance by ningalins and its use in drug combinations against human colon carcinoma xenograft in nude mice. | 2005 Oct |
2 |
| 19 |
15953199 | Selamectin is a potent substrate and inhibitor of human and canine P-glycoprotein. | 2005 Jun |
2 |
| 20 |
15248030 | Inhibition of P-glycoprotein activity and reversal of cancer multidrug resistance by Momordica charantia extract. | 2004 Dec |
1 |
| 21 |
12545143 | Dipyridamole enhances digoxin bioavailability via P-glycoprotein inhibition. | 2003 Jan |
1 |
| 22 |
12636153 | Isolation and characterization of Caco-2 subclones expressing high levels of multidrug resistance protein efflux transporter. | 2003 Feb |
2 |
| 23 |
12081145 | Cytotoxic effects of 27 anticancer drugs in HeLa and MDR1-overexpressing derivative cell lines. | 2002 Jun |
1 |
| 24 |
11411546 | Reversal of vinblastine resistance in human leukemic cells by haloperidol and dihydrohaloperidol. | 2001 Jun |
1 |
| 25 |
11561081 | Functional expression of P-glycoprotein in rat brain microglia. | 2001 Oct |
1 |
| 26 |
11642329 | Circumvention of acquired resistance to doxorubicin in K562 human leukemia cells by oxatomide. | 2001 Oct |
1 |
| 27 |
12375883 | Linker length in podophyllotoxin-acridine conjugates determines potency in vivo and in vitro as well as specificity against MDR cell lines. | 2001 Dec |
1 |
| 28 |
10739116 | Localization of the 1,4-dihydropyridine drug acceptor of P-glycoprotein to a cytoplasmic domain using a permanently charged derivative N-methyl dexniguldipine. | 2000 Mar |
3 |
| 29 |
10778983 | Synergistic effect of prochlorperazine and dipyridamole on the cellular retention and cytotoxicity of doxorubicin. | 2000 Apr |
1 |
| 30 |
11055337 | Synthesis and preliminary analysis of a P-glycoprotein-specific [3H]-benzophenone photoaffinity label based on (-)-stipiamide. | 2000 Oct 16 |
1 |
| 31 |
9862789 | Characterization of binding properties to human P-glycoprotein: development of a [3H]verapamil radioligand-binding assay. | 1999 Jan |
5 |
| 32 |
10576649 | The acridonecarboxamide GF120918 potently reverses P-glycoprotein-mediated resistance in human sarcoma MES-Dx5 cells. | 1999 Nov |
2 |
| 33 |
9538020 | Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state. | 1998 Apr 7 |
1 |
| 34 |
9700723 | Development of novel reversal agents, imidazothiazole derivatives, targeting MDR1- and MRP-mediated multidrug resistance. | 1998 |
1 |
| 35 |
9803961 | Interaction of anti-HIV protease inhibitors with the multidrug transporter P-glycoprotein (P-gp) in human cultured cells. | 1998 Nov 1 |
2 |
| 36 |
8960059 | Reversal of P-glycoprotein-associated multidrug resistance by ivermectin. | 1997 Jan 10 |
1 |
| 37 |
9207250 | Function of P-glycoprotein expressed in placenta and mole. | 1997 Jun 27 |
2 |
| 38 |
9434626 | Effects of multidrug resistance-related ATP-binding-cassette transporter proteins on the cytoskeletal activity of cytochalasins. | 1997 Dec 15 |
4 |
| 39 |
8567666 | Partial reversal of multidrug resistance in human breast cancer cells by an N-myristoylated protein kinase C-alpha pseudosubstrate peptide. | 1996 Jan 26 |
1 |
| 40 |
8635866 | Resistance to the chemosensitizer verapamil in a multi-drug-resistant (MDR) human multiple myeloma cell line. | 1996 May 16 |
2 |
| 41 |
8720592 | Interaction of cytostatics and chemosensitizers with the dexniguldipine binding site on P-glycoprotein. | 1996 Jan 11 |
2 |
| 42 |
8791998 | Detection of P-glycoprotein expression by tumoral cells with NBDL-CsA, a fluorescent derivative of cyclosporin A. | 1996 May |
1 |
| 43 |
8794885 | BIBW22 BS, potent multidrug resistance-reversing agent, binds directly to P-glycoprotein and accumulates in drug-resistant cells. | 1996 Sep |
1 |
| 44 |
9816222 | Cyclosporin A and PSC 833 prevent up-regulation of MDR1 expression by anthracyclines in a human multidrug-resistant cell line. | 1996 Apr |
1 |
| 45 |
7554042 | The activity of deoxyspergualin in multidrug-resistant cells. | 1995 |
2 |
| 46 |
7559420 | Characterization of prenylcysteines that interact with P-glycoprotein and inhibit drug transport in tumor cells. | 1995 Sep 29 |
1 |
| 47 |
7598747 | Allosteric regulation of [3H]vinblastine binding to P-glycoprotein of MCF-7 ADR cells by dexniguldipine. | 1995 Jun 16 |
2 |
| 48 |
7623771 | B9209-005, an azido derivative of the chemosensitizer dexniguldipine-HCl, photolabels P-glycoprotein. | 1995 Jul |
2 |
| 49 |
7631829 | Differential interaction of human renal P-glycoprotein with various metabolites and analogues of cyclosporin A. | 1995 Jul |
2 |
| 50 |
7632162 | Novel dithiane analogues of tiapamil with high activity to overcome multidrug resistance in vitro. | 1995 Jul 17 |
2 |