Title : Characterization of prenylcysteines that interact with P-glycoprotein and inhibit drug transport in tumor cells.

Pub. Date : 1995 Sep 29

PMID : 7559420






1 Functional Relationships(s)
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1 In studies using MDR1-transfected human breast cancer cells, the acetylated prenylcysteine analogs inhibit P-glycoprotein-mediated drug transport and enhance the steady-state accumulation of [3H]vinblastine, [3H]colchicine, and [3H]taxol. Tritium ATP binding cassette subfamily B member 1 Homo sapiens