| 1 |
35629245 | Evaluation of Pharmacogenetics of Drug-Metabolizing Enzymes and Drug Efflux Transporter in Renal Transplants Receiving Immunosuppressants. | 2022 May 19 |
1 |
| 2 |
32420174 | The effect of ABCB1 polymorphism on sirolimus in renal transplant recipients: a meta-analysis. | 2020 Apr |
12 |
| 3 |
31323368 | Rapamycin loaded TPGS-Lecithins-Zein nanoparticles based on core-shell structure for oral drug administration. | 2019 Sep 10 |
2 |
| 4 |
28355970 | Clinical impact and management of fluconazole discontinuation on sirolimus levels in bone marrow transplant patients. | 2018 Apr |
2 |
| 5 |
30324134 | Microphysiological 3D model of amyotrophic lateral sclerosis (ALS) from human iPS-derived muscle cells and optogenetic motor neurons. | 2018 Oct |
1 |
| 6 |
28186963 | An oral quinoline derivative, MPT0B392, causes leukemic cells mitotic arrest and overcomes drug resistant cancer cells. | 2017 Apr 25 |
2 |
| 7 |
28245187 | Influence of genetic polymorphisms of CYP3A5 and ABCB1 on sirolimus pharmacokinetics, patient and graft survival and other clinical outcomes in renal transplant. | 2017 Mar 1 |
1 |
| 8 |
28676933 | Association of NR1I2, CYP3A5 and ABCB1 genetic polymorphisms with variability of temsirolimus pharmacokinetics and toxicity in patients with metastatic bladder cancer. | 2017 Sep |
3 |
| 9 |
29061787 | (-)-Epigallocatechin-3-gallate Down-regulates Doxorubicin-induced Overexpression of P-glycoprotein Through the Coordinate Inhibition of PI3K/Akt and MEK/ERK Signaling Pathways. | 2017 Nov |
1 |
| 10 |
26036652 | Co-delivery of rapamycin- and piperine-loaded polymeric nanoparticles for breast cancer treatment. | 2016 Sep |
3 |
| 11 |
26325438 | Influence of Absorption, Distribution, Metabolism, and Excretion Genomic Variants on Tacrolimus/Sirolimus Blood Levels and Graft-versus-Host Disease after Allogeneic Hematopoietic Cell Transplantation. | 2016 Feb |
1 |
| 12 |
26924291 | Sirolimus induces apoptosis and reverses multidrug resistance in human osteosarcoma cells in vitro via increasing microRNA-34b expression. | 2016 Apr |
1 |
| 13 |
26543771 | CYP3A5 and ABCB1 genotype influence tacrolimus and sirolimus pharmacokinetics in renal transplant recipients. | 2015 |
1 |
| 14 |
24285256 | ABCB1 haplotype influences the sirolimus dose requirements in Chinese renal transplant recipients. | 2014 Apr |
3 |
| 15 |
23434829 | Upregulation of drug transporter expression by osteopontin in prostate cancer cells. | 2013 May |
1 |
| 16 |
23073467 | Associations of ABCB1 and IL-10 genetic polymorphisms with sirolimus-induced dyslipidemia in renal transplant recipients. | 2012 Nov 15 |
1 |
| 17 |
22016125 | [Drug interactions and immunosuppression in organ transplant recipients]. | 2011 Oct 18 |
1 |
| 18 |
22094953 | Associations of ABCB1 3435C>T and IL-10-1082G>A polymorphisms with long-term sirolimus dose requirements in renal transplant patients. | 2011 Dec 27 |
1 |
| 19 |
20220747 | Pharmacokinetic and pharmacodynamic interactions between the immunosuppressant sirolimus and the lipid-lowering drug ezetimibe in healthy volunteers. | 2010 Jun |
2 |
| 20 |
19557637 | Targeting mammalian target of rapamycin to both downregulate and disable the P-glycoprotein pump in multidrug-resistant B-cell lymphoma cell lines. | 2009 Jul |
1 |
| 21 |
19709321 | Effect of coadministered HIV-protease inhibitors on tacrolimus and sirolimus blood concentrations in a kidney transplant recipient. | 2009 Aug |
1 |
| 22 |
19728747 | Immunotherapy in elderly transplant recipients: a guide to clinically significant drug interactions. | 2009 |
1 |
| 23 |
17912526 | Antiproliferative effects of rapamycin as a single agent and in combination with carboplatin and paclitaxel in head and neck cancer cell lines. | 2008 Jul |
1 |
| 24 |
17941052 | Association study of ABCB1 and CYP3A5 gene polymorphisms with sirolimus trough concentration and dose requirements in Chinese renal transplant recipients. | 2008 Jan |
1 |
| 25 |
18594053 | Corticosteroid interactions with cyclosporine, tacrolimus, mycophenolate, and sirolimus: fact or fiction? | 2008 Jul |
2 |
| 26 |
17031644 | Differential effects of the immunosuppressive agents cyclosporin A, tacrolimus and sirolimus on drug transport by multidrug resistance proteins. | 2007 Jul |
9 |
| 27 |
17889118 | Pharmacogenetics of tacrolimus and sirolimus in renal transplant patients: from retrospective analyses to prospective studies. | 2007 Sep |
3 |
| 28 |
16837925 | Role of P-glycoprotein in cyclosporine cytotoxicity in the cyclosporine-sirolimus interaction. | 2006 Sep |
7 |
| 29 |
16911499 | Amiodarone-sirolimus/tacrolimus interaction in a pediatric heart transplant patient. | 2006 Sep |
1 |
| 30 |
15707415 | Consequences of genetic polymorphisms for sirolimus requirements after renal transplant in patients on primary sirolimus therapy. | 2005 Mar |
2 |
| 31 |
16249748 | Sirolimus and tacrolimus trough concentrations and dose requirements after kidney transplantation in relation to CYP3A5 and MDR1 polymorphisms and steroids. | 2005 Oct 15 |
2 |
| 32 |
15307840 | CYP3A4 and P-glycoprotein activity in healthy controls and transplant patients on cyclosporin vs. tacrolimus vs. sirolimus. | 2004 Sep |
3 |
| 33 |
15686733 | Clinical relevance of sirolimus drug interactions in transplant patients. | 2004 Dec |
1 |
| 34 |
15760093 | Exposure-response relationships and drug interactions of sirolimus. | 2004 Oct 15 |
2 |
| 35 |
12235265 | Sirolimus oral absorption in rats is increased by ketoconazole but is not affected by D-alpha-tocopheryl poly(ethylene glycol 1000) succinate. | 2002 Oct |
1 |
| 36 |
11762554 | P-glycoprotein (P-gp) is upregulated in peripheral T-cell subsets from solid organ transplant recipients. | 2001 Dec |
2 |
| 37 |
10516933 | P-glycoprotein and drug therapy in organ transplantation. | 1999 Oct |
1 |
| 38 |
9465841 | The effects of relative timing of sirolimus and cyclosporine microemulsion formulation coadministration on the pharmacokinetics of each agent. | 1998 Jan |
1 |
| 39 |
8668925 | Inhibition by rapamycin of P-glycoprotein 170-mediated export from normal lymphocytes. | 1996 Apr |
6 |
| 40 |
8702500 | Immunosuppressant target protein FKBP12 is required for P-glycoprotein function in yeast. | 1996 Aug 2 |
1 |
| 41 |
1381629 | Immunosuppressants FK506 and rapamycin function as reversal agents of the multidrug resistance phenotype. | 1992 Sep 15 |
1 |