Quercetin

ATP binding cassette subfamily B member 1 ; Homo sapiens







50 Article(s)
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1 32329631 Quercetin Triggers Induction of Apoptotic and Lysosomal Death of Sensitive and Multidrug Resistant Leukaemia HL60 Cells. 2021 2
2 33397267 Anti-MDR Effects of Quercetin and its Nanoemulsion in Multidrug-Resistant Human Leukemia Cells. 2021 2
3 33514009 Co-Amorphous Formulations of Furosemide with Arginine and P-Glycoprotein Inhibitor Drugs. 2021 Jan 27 2
4 34601070 Determination of effective concentrations of drug absorption enhancers using in vitro and ex vivo models. 2021 Dec 1 1
5 34959345 Effects of Polyphenols on P-Glycoprotein (ABCB1) Activity. 2021 Dec 2 2
6 32422185 Quercetin overcomes colon cancer cells resistance to chemotherapy by inhibiting solute carrier family 1, member 5 transporter. 2020 Aug 15 4
7 33052979 Quercetin potentializes the respective cytotoxic activity of gemcitabine or doxorubicin on 3D culture of AsPC-1 or HepG2 cells, through the inhibition of HIF-1α and MDR1. 2020 2
8 33306006 Quercetin acts as a P-gp modulator via impeding signal transduction from nucleotide-binding domain to transmembrane domain. 2020 Dec 11 5
9 30318192 Multifunctional quercetin conjugated chitosan nano-micelles with P-gp inhibition and permeation enhancement of anticancer drug. 2019 Jan 1 1
10 31593704 7-O-geranylquercetin contributes to reverse P-gp-mediated adriamycin resistance in breast cancer. 2019 Dec 1 2
11 29635751 Quercetin reversed MDR in breast cancer cells through down-regulating P-gp expression and eliminating cancer stem cells mediated by YB-1 nuclear translocation. 2018 Aug 1
12 29747752 Reversal effect of quercetin on multidrug resistance via FZD7/β-catenin pathway in hepatocellular carcinoma cells. 2018 Apr 1 5
13 30233175 Quercetin and doxorubicin co-delivery using mesoporous silica nanoparticles enhance the efficacy of gastric carcinoma chemotherapy. 2018 1
14 28043777 Quercetin-glutamic acid conjugate with a non-hydrolysable linker; a novel scaffold for multidrug resistance reversal agents through inhibition of P-glycoprotein. 2017 Feb 1 4
15 28462502 Mechanistically elucidating the in vitro safety and efficacy of a novel doxorubicin derivative. 2017 Aug 2
16 26366751 Vitamin D Receptor-Mediated Upregulation of CYP3A4 and MDR1 by Quercetin in Caco-2 cells. 2016 Jan 3
17 27216424 Screening dietary flavonoids for the reversal of P-glycoprotein-mediated multidrug resistance in cancer. 2016 Jul 19 2
18 27572418 Quercetin affects glutathione levels and redox ratio in human aortic endothelial cells not through oxidation but formation and cellular export of quercetin-glutathione conjugates and upregulation of glutamate-cysteine ligase. 2016 Oct 3
19 27652191 Natural flavonoids silymarin and quercetin improve the brain distribution of co-administered P-gp substrate drugs. 2016 5
20 25339540 Quercetin enhances adriamycin cytotoxicity through induction of apoptosis and regulation of mitogen-activated protein kinase/extracellular signal-regulated kinase/c-Jun N-terminal kinase signaling in multidrug-resistant leukemia K562 cells. 2015 Jan 1
21 25687049 [Effect of quercetin on doxorubicin-induced expression of MDR1 gene in HL-60 cells]. 2015 Feb 6
22 26141765 Quercetin-POM (pivaloxymethyl) conjugates: Modulatory activity for P-glycoprotein-based multidrug resistance. 2015 Jul 15 1
23 26238175 3-Hydroxyflavone and structural analogues differentially activate pregnane X receptor: Implication for inflammatory bowel disease. 2015 Oct 2
24 24362044 Transport of active flavonoids, based on cytotoxicity and lipophilicity: an evaluation using the blood-brain barrier cell and Caco-2 cell models. 2014 Apr 2
25 24472704 Effect of single-dose and short-term administration of quercetin on the pharmacokinetics of talinolol in humans - Implications for the evaluation of transporter-mediated flavonoid-drug interactions. 2014 Sep 30 2
26 25122155 Water-soluble and cleavable quercetin-amino acid conjugates as safe modulators for P-glycoprotein-based multidrug resistance. 2014 Sep 11 1
27 22721393 The effect of quercetin on doxorubicin cytotoxicity in human breast cancer cells. 2013 Feb 1
28 23422925 Effect of quercetin on P-glycoprotein transport ability in Chinese healthy subjects. 2013 Apr 5
29 21247706 Can flavonoids from honey alter multidrug resistance? 2011 Apr 1
30 21466223 Quercetin and rutin reduced the bioavailability of cyclosporine from Neoral, an immunosuppressant, through activating P-glycoprotein and CYP 3A4. 2011 May 11 3
31 20335952 Quercetin as a potential modulator of P-glycoprotein expression and function in cells of human pancreatic carcinoma line resistant to daunorubicin. 2010 Feb 9 1
32 19034627 Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug-metabolizing enzymes through pregnane X receptor, constitutive androstane receptor, and aryl hydrocarbon receptor-mediated pathways. 2009 Apr 1
33 19221726 Short-term effect of quercetin on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein, in healthy volunteers. 2009 Jun 4
34 18624906 Activation of beta-catenin signalling by GSK-3 inhibition increases p-glycoprotein expression in brain endothelial cells. 2008 Aug 1
35 18951251 Effects of dietary flavonoids on the transport of cimetidine via P-glycoprotein and cationic transporters in Caco-2 and LLC-PK1 cell models. 2008 Dec 1
36 16442130 MDR- and CYP3A4-mediated drug-herbal interactions. 2006 Mar 27 1
37 16945047 Effect of quercetin on the plasma and intracellular concentrations of saquinavir in healthy adults. 2006 Sep 1
38 15828450 Inhibition of P-glycoprotein function and expression by kaempferol and quercetin. 2005 Feb 2
39 15905060 Simultaneous determination of quercetin, kaempferol and isorhamnetin accumulated human breast cancer cells, by high-performance liquid chromatography. 2005 Sep 1 1
40 16059641 Flavonoid quercetin, but not apigenin or luteolin, induced apoptosis in human myeloid leukemia cells and their resistant variants. 2005 1
41 15072439 Herbal modulation of P-glycoprotein. 2004 Feb 2
42 15112361 Establishment of a P-glycoprotein substrate screening model and its preliminary application. 2004 May 1 3
43 15266218 In vitro interaction of the HIV protease inhibitor ritonavir with herbal constituents: changes in P-gp and CYP3A4 activity. 2004 Jul-Aug 1
44 12485947 Bioflavonoid stimulation of glutathione transport by the 190-kDa multidrug resistance protein 1 (MRP1). 2003 Jan 1
45 12969528 [Expression of HSP70 and P-glycoprotein (P-gp) in human hepatocarcinoma HepG2 cells induced by heat shock and inhibiting effect of quercetin on them]. 2003 Sep 6
46 11809535 Inhibition of P-glycoprotein by flavonoid derivatives in adriamycin-resistant human myelogenous leukemia (K562/ADM) cells. 2002 Mar 8 1
47 11306701 Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and atpase activities by interaction with dietary flavonoids. 2001 May 3
48 7923555 Quercetin potentiates the effect of adriamycin in a multidrug-resistant MCF-7 human breast-cancer cell line: P-glycoprotein as a possible target. 1994 3
49 7903198 Flavonol-stimulated efflux of 7,12-dimethylbenz(a)anthracene in multidrug-resistant breast cancer cells. 1993 Dec 15 2
50 1349537 Quercetin, a bioflavonoid, inhibits the increase of human multidrug resistance gene (MDR1) expression caused by arsenite. 1992 Apr 27 5