9 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 16763681 | Multipolar interactions in the D pocket of thrombin: large differences between tricyclic imide and lactam inhibitors. | 2006 Jun 21 | 5 |
2 | 15305203 | Nucleophilic trifluoromethylation of cyclic imides using (trifluoromethyl)trimethylsilane CF3SiMe3. | 2004 Aug 21 | 1 |
3 | 11720865 | Novel bicyclic lactam inhibitors of thrombin: potency and selectivity optimization through P1 residues. | 2001 Dec 17 | 1 |
4 | 11063627 | Hydrolytic stability versus ring size in lactams: implications for the development of lactam antibiotics and other serine protease inhibitors. | 2000 Nov 2 | 3 |
5 | 10206546 | Potent and selective bicyclic lactam inhibitors of thrombin: Part 3: P1' modifications. | 1999 Mar 22 | 1 |
6 | 10230610 | Synthesis and structure-activity relationship of potent bicyclic lactam thrombin inhibitors. | 1999 Apr 5 | 1 |
7 | 9873743 | Potent and selective bicyclic lactam inhibitors of thrombin: Part 2: P1 modifications. | 1998 Dec 1 | 1 |
8 | 9934495 | Alkoxide-catalyzed ring-opening of a novel homosaccharin derivative: synthesis of potent, selective P3-lactam thrombin inhibitors containing P4-o-alkoxycarbonylbenzylsulfonamide residues. | 1998 Dec 15 | 1 |
9 | 8536341 | Lactam-conformationally restricted analogs of N alpha-arylsulfonyl arginine amide: design, synthesis and inhibitory activity toward thrombin and related enzymes. | 1995 Oct | 1 |