Lactams

coagulation factor II, thrombin ; Homo sapiens







9 Article(s)
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Title
Pub. Year
#Total Relationships
1 16763681 Multipolar interactions in the D pocket of thrombin: large differences between tricyclic imide and lactam inhibitors. 2006 Jun 21 5
2 15305203 Nucleophilic trifluoromethylation of cyclic imides using (trifluoromethyl)trimethylsilane CF3SiMe3. 2004 Aug 21 1
3 11720865 Novel bicyclic lactam inhibitors of thrombin: potency and selectivity optimization through P1 residues. 2001 Dec 17 1
4 11063627 Hydrolytic stability versus ring size in lactams: implications for the development of lactam antibiotics and other serine protease inhibitors. 2000 Nov 2 3
5 10206546 Potent and selective bicyclic lactam inhibitors of thrombin: Part 3: P1' modifications. 1999 Mar 22 1
6 10230610 Synthesis and structure-activity relationship of potent bicyclic lactam thrombin inhibitors. 1999 Apr 5 1
7 9873743 Potent and selective bicyclic lactam inhibitors of thrombin: Part 2: P1 modifications. 1998 Dec 1 1
8 9934495 Alkoxide-catalyzed ring-opening of a novel homosaccharin derivative: synthesis of potent, selective P3-lactam thrombin inhibitors containing P4-o-alkoxycarbonylbenzylsulfonamide residues. 1998 Dec 15 1
9 8536341 Lactam-conformationally restricted analogs of N alpha-arylsulfonyl arginine amide: design, synthesis and inhibitory activity toward thrombin and related enzymes. 1995 Oct 1