Title : Hydrolytic stability versus ring size in lactams: implications for the development of lactam antibiotics and other serine protease inhibitors.

Pub. Date : 2000 Nov 2

PMID : 11063627






3 Functional Relationships(s)
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1 Hydrolytic stability versus ring size in lactams: implications for the development of lactam antibiotics and other serine protease inhibitors. Lactams coagulation factor II, thrombin Homo sapiens
2 Hydrolytic stability versus ring size in lactams: implications for the development of lactam antibiotics and other serine protease inhibitors. Lactams coagulation factor II, thrombin Homo sapiens
3 The study highlights the as yet overlooked six-membered lactam ring as a promising vantage point for the development of new classes of antiinfectives and other serine protease inhibitors. Lactams coagulation factor II, thrombin Homo sapiens