| 1 |
32556284 | A case of thrombomodulin mutation causing defective thrombin binding with absence of protein C and TAFI activation. | 2020 Jun 23 |
1 |
| 2 |
28302935 | Factor X Deficiency with Heterozygous Mutations of Novel p.G435S and Known p.G244R in a Patient Presenting with Severe Umbilical Hemorrhage. | 2017 Apr 13 |
1 |
| 3 |
22612268 | Ligand binding stepwise disrupts water network in thrombin: enthalpic and entropic changes reveal classical hydrophobic effect. | 2012 Jul 12 |
1 |
| 4 |
20071328 | Osteopontin is cleaved at multiple sites close to its integrin-binding motifs in milk and is a novel substrate for plasmin and cathepsin D. | 2010 Mar 12 |
1 |
| 5 |
20148533 | Enhancement of hydrophobic interactions and hydrogen bond strength by cooperativity: synthesis, modeling, and molecular dynamics simulations of a congeneric series of thrombin inhibitors. | 2010 Mar 11 |
1 |
| 6 |
20233000 | Glycine pretreatment ameliorates liver injury after partial hepatectomy in the rat. | 2010 Feb |
1 |
| 7 |
20236938 | Crystal structure of thrombin bound to the uncleaved extracellular fragment of PAR1. | 2010 May 14 |
1 |
| 8 |
19715676 | Role of P2 glycine in determining the specificity of antithrombin reaction with coagulation proteases. | 2009 Nov 6 |
1 |
| 9 |
19846563 | Mutant N143P reveals how Na+ activates thrombin. | 2009 Dec 25 |
1 |
| 10 |
18585267 | Tryptophan-contained peptide-functional nanomaterials as general spectrofluorometric reagents for enzyme. | 2008 Jun 30 |
12 |
| 11 |
17473569 | Effect of glycine on the calcium signal of thrombin-stimulated platelets. | 2007 Jun |
3 |
| 12 |
16797105 | The biological activity of the histidine-containing diketopiperazines cyclo(His-Ala) and cyclo(His-Gly). | 2006 Nov |
1 |
| 13 |
15890651 | Energetic and structural consequences of perturbing Gly-193 in the oxyanion hole of serine proteases. | 2005 Jul 8 |
2 |
| 14 |
15998637 | Thrombin functions through its RGD sequence in a non-canonical conformation. | 2005 Aug 19 |
1 |
| 15 |
14962227 | Prothrombin Shanghai: hypoprothrombinaemia caused by substitution of Gla29 by Gly. | 2004 Jan |
2 |
| 16 |
12731874 | Thermodynamic characterization of the binding of nucleotides to glycyl-tRNA synthetase. | 2003 May 13 |
1 |
| 17 |
12916152 | [Human thrombin: enzymatic properties, stability and standardization of preparation]. | 2002 Sep-Oct |
1 |
| 18 |
11601677 | Fast homogeneous assay for plasma procarboxypeptidase U. | 2001 Sep |
1 |
| 19 |
10801785 | Examining thrombin hydrolysis of the factor XIII activation peptide segment leads to a proposal for explaining the cardioprotective effects observed with the factor XIII V34L mutation. | 2000 Jul 7 |
1 |
| 20 |
11080374 | Evolution of serpin specificity: cooperative interactions in the reactive-site loop sequence of antithrombin specifically restrict the inhibition of activated protein C. | 2000 Nov |
1 |
| 21 |
10497166 | Importance of the P2 glycine of antithrombin in target proteinase specificity, heparin activation, and the efficiency of proteinase trapping as revealed by a P2 Gly --> Pro mutation. | 1999 Oct 1 |
1 |
| 22 |
9490687 | Prothrombin Greenville, Arg517-->Gln, identified in an individual heterozygous for dysprothrombinemia. | 1998 Mar 15 |
1 |
| 23 |
9790668 | Allosteric effects of a monoclonal antibody against thrombin exosite II. | 1998 Oct 27 |
1 |
| 24 |
9200692 | Role of Leu99 of thrombin in determining the P2 specificity of serpins. | 1997 Jun 17 |
2 |
| 25 |
9005443 | Construction and structure-activity relationships of chimeric prourokinase derivatives with intrinsic thrombin-inhibitory potential. | 1996 Feb |
2 |
| 26 |
7548057 | Intermolecular interactions between protein C inhibitor and coagulation proteases. | 1995 Oct 10 |
1 |
| 27 |
7582983 | Peptide-derived transition state analogue inhibitors of thrombin; synthesis, activity and selectivity. | 1995 Aug |
1 |
| 28 |
7744836 | Development of a novel recombinant serpin with potential antithrombotic properties. | 1995 May 19 |
2 |
| 29 |
21043620 | The Fluid-phase SC5b-9 Terminal Complement Complex Binds to the GPIIb/IIIa Complex of Thrombin-stimulated Human Blood Platelets Inhibiting Platelet Aggregation. | 1995 |
1 |
| 30 |
7756983 | The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin. | 1994 Dec |
1 |
| 31 |
8206990 | Mutagenesis of recombinant protein C inhibitor reactive site residues alters target proteinase specificity. | 1994 Jun 17 |
1 |
| 32 |
8136018 | Interaction of thrombin with antithrombin, heparin cofactor II, and protein C inhibitor. | 1993 Dec |
2 |
| 33 |
8384827 | Importance of the Arg-Gly-Asp triplet in human thrombin for maintenance of structure and function. | 1993 Mar |
2 |
| 34 |
8415574 | The structure of a designed peptidomimetic inhibitor complex of alpha-thrombin. | 1993 Jul |
1 |
| 35 |
1290488 | Thrombin-specific inhibition by and slow cleavage of hirulog-1. | 1992 May 1 |
1 |
| 36 |
1547341 | Antithrombin-III-Stockholm: a codon 392 (Gly----Asp) mutation with normal heparin binding and impaired serine protease reactivity. | 1992 Mar 15 |
1 |
| 37 |
1560020 | The structure of residues 7-16 of the A alpha-chain of human fibrinogen bound to bovine thrombin at 2.3-A resolution. | 1992 Apr 15 |
1 |
| 38 |
1581297 | Thrombin hydrolysis of an N-terminal peptide from fibrinogen Lille: kinetic and NMR studies. | 1992 May 12 |
2 |
| 39 |
1631048 | Characterization of the interactions of a bifunctional inhibitor with alpha-thrombin by molecular modelling and peptide synthesis. | 1992 Jan |
1 |
| 40 |
1643115 | Diphosphorylation of platelet myosin ex vivo in the initial phase of activation by thrombin. | 1992 Jul 22 |
1 |
| 41 |
1871715 | A photometric assay for blood coagulation factor XIII. | 1991 May 6 |
1 |
| 42 |
1988465 | An Arg-Gly-Asp sequence within thrombin promotes endothelial cell adhesion. | 1991 Jan |
1 |
| 43 |
2369894 | Recombinant human protein C derivatives: altered response to calcium resulting in enhanced activation by thrombin. | 1990 Aug |
2 |
| 44 |
2719946 | Substitution of valine for glycine-558 in the congenital dysthrombin thrombin Quick II alters primary substrate specificity. | 1989 Mar 7 |
1 |
| 45 |
2742826 | High-resolution NMR studies of fibrinogen-like peptides in solution: interaction of thrombin with residues 1-23 of the A alpha chain of human fibrinogen. | 1989 Apr 4 |
3 |
| 46 |
2742827 | High-resolution NMR studies of fibrinogen-like peptides in solution: structure of a thrombin-bound peptide corresponding to residues 7-16 of the A alpha chain of human fibrinogen. | 1989 Apr 4 |
1 |
| 47 |
2742828 | High-resolution NMR studies of fibrinogen-like peptides in solution: structural basis for the bleeding disorder caused by a single mutation of Gly(12) to Val(12) in the A alpha chain of human fibrinogen Rouen. | 1989 Apr 4 |
3 |
| 48 |
2928328 | Tyrosine-specific protein phosphorylation is regulated by glycoprotein IIb-IIIa in platelets. | 1989 Apr |
3 |
| 49 |
3071528 | A characteristic property of vitamin K-dependent plasma protein Z. | 1988 Sep |
1 |
| 50 |
3166991 | High-resolution NMR studies of fibrinogen-like peptides in solution: resonance assignments and conformational analysis of residues 1-23 of the A alpha chain of human fibrinogen. | 1988 Jun 14 |
1 |