Ceramides

tumor necrosis factor ; Homo sapiens







240 Article(s)
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51 16730193 TNF-alpha-induced impairment of mitochondrial integrity and apoptosis mediated by caspase-8 in adult ventricular myocytes. 2006 Apr 1
52 16754199 Ceramide mediates TNF-alpha-induced insulin resistance on GLUT4 gene expression in brown adipocytes. 2006 Feb 7
53 16787207 Ceramide in apoptotic signaling and anticancer therapy. 2006 1
54 16979119 Inhibition of IL-8 release from CFTR-deficient lung epithelial cells following pre-treatment with fenretinide. 2006 Nov 1
55 17069807 Phospholipase D protects ECV304 cells against TNFalpha-induced apoptosis. 2006 Nov 13 1
56 15516208 A mitochondrial pool of sphingomyelin is involved in TNFalpha-induced Bax translocation to mitochondria. 2005 Mar 15 3
57 15721320 Tumor necrosis factor (TNF) interferes with insulin signaling through the p55 TNF receptor death domain. 2005 Apr 1 1
58 15816837 Interleukin-4 suppresses the enhancement of ceramide synthesis and cutaneous permeability barrier functions induced by tumor necrosis factor-alpha and interferon-gamma in human epidermis. 2005 Apr 2
59 16033420 Amyloid-beta peptide enhances tumor necrosis factor-alpha-induced iNOS through neutral sphingomyelinase/ceramide pathway in oligodendrocytes. 2005 Aug 1
60 16344602 Ceramide, tumor necrosis factor and alcohol-induced liver disease. 2005 Nov 1
61 15023539 Distinct stress and cell destruction pathways are engaged by TNF and ceramide during apoptosis of MCF-7 cells. 2004 Apr 1 5
62 15131591 Molecular mechanisms of TNF-alpha-induced ceramide formation in human glioma cells: P53-mediated oxidant stress-dependent and -independent pathways. 2004 Sep 4
63 15157676 Ceramide-induced enhancement of secretory phospholipase A2 expression via generation of reactive oxygen species in tumor necrosis factor-alpha-stimulated mesangial cells. 2004 Aug 2
64 15256490 Proinflammatory cytokine impairment of insulin-like growth factor I-induced protein synthesis in skeletal muscle myoblasts requires ceramide. 2004 Oct 1
65 15273737 Tumor necrosis factor alpha sensitizes malignant cells to chemotherapeutic drugs via the mitochondrial apoptosis pathway independently of caspase-8 and NF-kappaB. 2004 Sep 2 2
66 15322180 Ceramide inhibits IL-2 production by preventing protein kinase C-dependent NF-kappaB activation: possible role in protein kinase Ctheta regulation. 2004 Sep 1 1
67 15469694 Protective role of tissue transglutaminase in the cell death induced by TNF-alpha in SH-SY5Y neuroblastoma cells. 2004 Mar 31 1
68 15563986 TNFalpha reduces the expression of peroxisome proliferator-activated receptor gamma (PPARgamma) via the production of ceramide and activation of atypical PKC. 2004 Dec 3
69 12532151 Cell-permeable ceramides increase basal glucose incorporation into triacylglycerols but decrease the stimulation by insulin in 3T3-L1 adipocytes. 2003 Jan 2
70 12606947 Adenosine suppresses activation of nuclear factor-kappaB selectively induced by tumor necrosis factor in different cell types. 2003 Feb 27 1
71 12644590 Activation of endothelial nitric-oxide synthase by tumor necrosis factor-alpha: a novel pathway involving sequential activation of neutral sphingomyelinase, phosphatidylinositol-3' kinase, and Akt. 2003 Apr 2
72 12646059 Signaling mechanisms in tumor necrosis factor alpha-induced death of microvascular endothelial cells of the corpus luteum. 2003 Feb 11 2
73 12688321 Activation of protein kinase C enhances TNF-alpha-induced differentiation by preventing apoptosis via rapid up-regulation of c-Myc protein expression in HL-60 cells. 2003 Mar 1
74 12700652 Role of ceramide in mediating apoptosis of irradiated LNCaP prostate cancer cells. 2003 Feb 5
75 12721293 Uptake and metabolism of low density lipoproteins with elevated ceramide content by human microvascular endothelial cells: implications for the regulation of apoptosis. 2003 Jul 18 1
76 12738796 Cross-talk between JNK/SAPK and ERK/MAPK pathways: sustained activation of JNK blocks ERK activation by mitogenic factors. 2003 Jul 18 1
77 12959973 Intratesticular delivery of tumor necrosis factor-alpha and ceramide directly abrogates steroidogenic acute regulatory protein expression and Leydig cell steroidogenesis in adult rats. 2003 Nov 1
78 14563412 Saturated free fatty acid release and intracellular ceramide generation during apoptosis induction are closely related processes. 2003 Oct 20 1
79 14569872 [TNF-induced apoptosis and necrosis in myeloleukemia cells HL-60 is regulated by reactive oxygen metabolites depending on a cell cycle phase]. 2003 Jan-Feb 1
80 14708343 [Sphingolipid-mediated apoptotic signaling pathways]. 2003 1
81 14995068 Differential involvement of ceramide in TNFalpha-mediated activation of NF-kappaB in primary human keratinocytes and HaCaT keratinocytes. 2003 5
82 15041894 Alcohol-induced liver disease: when fat and oxidative stress meet. 2003 Apr-Jun 1
83 11815603 Involvement of sphingosine kinase in TNF-alpha-stimulated tetrahydrobiopterin biosynthesis in C6 glioma cells. 2002 Apr 12 3
84 11823712 TNF-alpha-induced tolerance to ischemic injury involves differential control of NF-kappaB transactivation: the role of NF-kappaB association with p300 adaptor. 2002 Feb 4
85 11872660 C(2)-ceramide influences the expression and insulin-mediated regulation of cyclic nucleotide phosphodiesterase 3B and lipolysis in 3T3-L1 adipocytes. 2002 Mar 1
86 12154098 Inhibition of tumor necrosis factor-induced cell death in MCF7 by a novel inhibitor of neutral sphingomyelinase. 2002 Oct 25 1
87 12208520 Ceramide generated by acidic sphingomyelinase contributes to tumor necrosis factor-alpha-mediated apoptosis in human colon HT-29 cells through glycosphingolipids formation. Possible role of ganglioside GD3. 2002 Aug 28 1
88 12387875 Bcl-xL interrupts oxidative activation of neutral sphingomyelinase. 2002 Oct 23 1
89 12404124 Cyclic GMP-dependent inhibition of acid sphingomyelinase by nitric oxide: an early step in protection against apoptosis. 2002 Nov 1
90 12419308 Modulation of CYP3A4 expression by ceramide in human colon carcinoma HT-29 cells. 2002 Nov 15 2
91 12473262 Gold sodium thiomalate (GSTM) inhibits lipopolysaccharide stimulated tumor necrosis factor-alpha through ceramide pathway. 2002 Sep 6
92 11085984 Activation of the endothelial nitric-oxide synthase by tumor necrosis factor-alpha. A novel feedback mechanism regulating cell death. 2001 Mar 2 1
93 11179444 Tumor necrosis factor-alpha-induced cyclooxygenase-2 expression via sequential activation of ceramide-dependent mitogen-activated protein kinases, and IkappaB kinase 1/2 in human alveolar epithelial cells. 2001 Mar 2
94 11282082 Loss of cyclin A and G1-cell cycle arrest are a prerequisite of ceramide-induced toxicity in human arterial endothelial cells. 2001 Apr 1
95 11336794 Daunorubicin attenuates tumor necrosis factor-alpha-induced biosynthesis of plasminogen activator inhibitor-1 in human umbilical vein endothelial cells. 2001 Apr 23 3
96 11404252 Sphingomyelin metabolites inhibit sphingomyelin synthase and CTP:phosphocholine cytidylyltransferase. 2001 Jul 1
97 11404253 CTP:phosphocholine cytidylyltransferase inhibition by ceramide via PKC-alpha, p38 MAPK, cPLA2, and 5-lipoxygenase. 2001 Jul 2
98 11413232 Cytokine-induced cell death in immortalized Schwann cells: roles of nitric oxide and cyclic AMP. 2001 Jun 2
99 11415943 Rapid reactive oxygen species production by mitochondria in endothelial cells exposed to tumor necrosis factor-alpha is mediated by ceramide. 2001 Jun 2
100 11435466 Involvement of FAN in TNF-induced apoptosis. 2001 Jul 1