4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole

tumor necrosis factor ; Homo sapiens







36 Article(s)
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1 34237962 Silencing of LncRNA-PVT1 ameliorates lipopolysaccharide-induced inflammation in THP-1-derived macrophages via inhibition of the p38 MAPK signaling pathway. 2021 Jun 1
2 31539804 Advanced oxidation protein products increase TNF-α and IL-1β expression in chondrocytes via NADPH oxidase 4 and accelerate cartilage degeneration in osteoarthritis progression. 2020 Jan 1
3 28170408 TNFα alters occludin and cerebral endothelial permeability: Role of p38MAPK. 2017 3
4 25834353 Mechanism of Macrophage-Derived Chemokine/CCL22 Production by HaCaT Keratinocytes. 2015 Apr 1
5 26358221 TNF-α-induced p38MAPK activation regulates TRPA1 and TRPV4 activity in odontoblast-like cells. 2015 Nov 2
6 24487964 TNF-α induces CXCL1 chemokine expression and release in human vascular endothelial cells in vitro via two distinct signaling pathways. 2014 Mar 1
7 24696473 Epstein-Barr virus infection induces indoleamine 2,3-dioxygenase expression in human monocyte-derived macrophages through p38/mitogen-activated protein kinase and NF-κB pathways: impairment in T cell functions. 2014 Jun 1
8 25530682 LPS- and LTA-induced expression of IL-6 and TNF-α in neonatal and adult blood: role of MAPKs and NF-κB. 2014 1
9 23965971 UVB-stimulated TNFα release from human melanocyte and melanoma cells is mediated by p38 MAPK. 2013 Aug 19 2
10 24069158 TNF-α induces cytosolic phospholipase A2 expression in human lung epithelial cells via JNK1/2- and p38 MAPK-dependent AP-1 activation. 2013 1
11 22729740 Up-regulation of interferon-stimulated gene15 and its conjugates by tumor necrosis factor-α via type I interferon-dependent and -independent pathways. 2012 Sep 2
12 20798552 Lipopolysaccharide-induced expression of Th1/Th2 cytokines in whole neonatal cord and adult blood: role of nuclear factor-kappa B and p38 MAPK. 2011 1
13 21388428 MAPKs ERK and p38, but not JNK phosphorylation, modulate IL-6 and TNF-α secretion following OK-432 in vitro stimulation of purified human monocytes. 2011 Aug 1
14 20039412 Involvement of MAPKs and NF-kappaB in tumor necrosis factor alpha-induced vascular cell adhesion molecule 1 expression in human rheumatoid arthritis synovial fibroblasts. 2010 Jan 1
15 18675993 The role of P38 MAPK and PKC in BLP induced TNF-alpha release, apoptosis, and NFkappaB activation in THP-1 monocyte cells. 2009 Jan 2
16 19583958 p38 MAPK inhibition selectively mitigates inflammatory mediators and VEGF production in AF cells co-cultured with activated macrophage-like THP-1 cells. 2009 Dec 1
17 18086809 p38 mitogen-activated protein kinase mediates lipopolysaccharide and tumor necrosis factor alpha induction of shiga toxin 2 sensitivity in human umbilical vein endothelial cells. 2008 Mar 2
18 17433832 Mitogen-activated protein kinase proteins regulate LPS-stimulated release of pro-inflammatory cytokines and prostaglandins from human gestational tissues. 2007 Aug-Sep 1
19 17591882 p38 MAP kinase pathway and stromelysin regulation in trabecular meshwork cells. 2007 Jul 1
20 17617469 Involvement of p38 MAP kinase in lipopolysaccharide-induced production of pro- and anti-inflammatory cytokines and prostaglandin E(2) in human choriodecidua. 2007 Oct 2
21 17902045 Induction of TNF-alpha by LPS in Schwann cell is regulated by MAPK activation signals. 2007 Nov 1
22 15703956 Inhibition of NF-kappaB renders human juvenile costal chondrocyte cell lines sensitive to TNF-alpha-mediated cell death. 2006 Jan 1
23 16202406 JNK and ERK MAP kinases mediate induction of IL-1beta, TNF-alpha and IL-8 following hyperosmolar stress in human limbal epithelial cells. 2006 Apr 1
24 16288471 Transcriptional regulation of VCAM-1 expression by tumor necrosis factor-alpha in human tracheal smooth muscle cells: involvement of MAPKs, NF-kappaB, p300, and histone acetylation. 2006 Apr 1
25 16424170 Protein expression of TNF-alpha in psoriatic skin is regulated at a posttranscriptional level by MAPK-activated protein kinase 2. 2006 Feb 1 1
26 15700318 Potential attenuation of p38 signaling by DDB2 as a factor in acquired TNF resistance. 2005 Jun 20 1
27 16117790 Mechanism of thymus- and activation-regulated chemokine (TARC)/CCL17 production and its modulation by roxithromycin. 2005 Sep 1
28 16314440 TNF-alpha-induced chemokine production and apoptosis in human neural precursor cells. 2005 Dec 1
29 14751545 Tumor necrosis factor-alpha-induced cyclooxygenase-2 expression in human tracheal smooth muscle cells: involvement of p42/p44 and p38 mitogen-activated protein kinases and nuclear factor-kappaB. 2004 May 1
30 12844496 Rho inhibition decreases TNF-induced endothelial MAPK activation and monolayer permeability. 2003 Nov 1
31 12089369 Phosphatidylinositol 3-kinase controls antineutrophil cytoplasmic antibodies-induced respiratory burst in human neutrophils. 2002 Jul 2
32 12160518 Downregulation of angiotensin converting enzyme by TNF-alpha in differentiating human macrophages. 2002 Jun 21 1
33 11455208 Downregulation of angiotensin-converting enzyme by tumor necrosis factor-alpha and interleukin-1beta in cultured human endothelial cells. 2001 Jul-Aug 1
34 10836611 TNF-alpha and serum induce SKALP/elafin gene expression in human keratinocytes by a p38 MAP kinase-dependent pathway. 2000 Apr 1
35 11028544 TNFalpha-induced suppression of PMN apoptosis is mediated through interleukin-8 production. 2000 Sep 1
36 10358198 Alcohol (ethanol) inhibits IL-8 and TNF: role of the p38 pathway. 1999 Jun 15 1