Pub. Date : 2002 Jul
PMID : 12089369
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | p38 MAPK inhibition with 10 microM SB202190 that also decreased ANCA-induced superoxide generation prevented S473 phosphorylation of Akt in response to TNF-alpha and to ANCA. | 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole | tumor necrosis factor | Homo sapiens |
| 2 | However, SB202190 but not LY294002 abrogated TNF-alpha-mediated ANCA antigen surface translocation, demonstrating that superoxide generation and ANCA antigen translocation proceed by separate mechanisms. | 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole | tumor necrosis factor | Homo sapiens |