Title : Statins prevent NF-kappaB transactivation independently of the IKK-pathway in human endothelial cells.

Pub. Date : 2006 Apr

PMID : 16051251






1 Functional Relationships(s)
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1 As observed with statins, inhibition of PI3-kinase activity by Ly294002 also blocked TNF-alpha-induced p65 translocation, but did not prevent IkappaBalpha phosphorylation nor IkappaBalpha degradation. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one tumor necrosis factor Homo sapiens