2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one

transforming growth factor beta 1 ; Homo sapiens







54 Article(s)
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1 32705806 Andrographolide attenuates epithelial-mesenchymal transition induced by TGF-β1 in alveolar epithelial cells. 2020 Sep 1
2 31389582 Silenced miR-21 inhibits renal interstitial fibrosis via targeting ERK1/2 signaling pathway in mice. 2019 Aug 1
3 31831776 ERK1/2 drives IL-1β-induced expression of TGF-β1 and BMP-2 in torn tendons. 2019 Dec 12 1
4 29215709 The potential role of aquaporin 1 on aristolochic acid I induced epithelial mesenchymal transition on HK-2 cells. 2018 Jun 1
5 30377686 [LIMR is involved in the inhibitory effect of antiflammin-1 on epithelial-mesenchymal transition in A549 cells]. 2018 Oct 25 1
6 26922429 Epigallocatechin-3-gallate inhibits transforming-growth-factor-β1-induced collagen synthesis by suppressing early growth response-1 in human buccal mucosal fibroblasts. 2017 Feb 1
7 28347704 High glucose induced endothelial to mesenchymal transition in human umbilical vein endothelial cell. 2017 Jun 1
8 26657209 Identification of intracellular pathways through which TGF-β1 upregulates URG-4/URGCP gene expression in hepatoma cells. 2016 Jan 1 1
9 22674629 Naringenin inhibits extracellular matrix production via extracellular signal-regulated kinase pathways in nasal polyp-derived fibroblasts. 2013 Mar 1
10 23468994 TGF-β-elicited induction of tissue inhibitor of metalloproteinases (TIMP)-3 expression in fibroblasts involves complex interplay between Smad3, p38α, and ERK1/2. 2013 1
11 23500539 Thalidomide inhibits fibronectin production in TGF-β1-treated normal and keloid fibroblasts via inhibition of the p38/Smad3 pathway. 2013 Jun 1 1
12 24405819 Pleiotropic effects of cancer cells' secreted factors on human stromal (mesenchymal) stem cells. 2013 Sep 17 2
13 21971976 Up-regulation of TGF-β via the activation of extracellular signal-regulated kinase 1 and 2 induced by prorenin in human renal mesangial cells. 2012 Jan 1
14 22217516 Soy peptide-induced stem cell proliferation: involvement of ERK and TGF-β1. 2012 Oct 2
15 22214163 [The effect of extracellular signal-regulated kinase 1/2 signaling pathway on the expression of transforming growth factor-beta1 in lung fibroblast activated by silicon dioxide]. 2011 Jul 4
16 19862801 Both nongenomic and genomic effects are involved in estradiol's enhancing the phenotype of smooth muscle cells in cultured prostate stromal cells. 2010 Feb 15 1
17 19923143 Bradykinin and high glucose promote renal tubular inflammation. 2010 Mar 2
18 20392803 Cyclic stretch induces proliferation and TGF-beta1-mediated apoptosis via p38 and ERK in ureteric bud cells. 2010 Sep 2
19 19243022 Transforming growth factor-beta induces CD44 cleavage that promotes migration of MDA-MB-435s cells through the up-regulation of membrane type 1-matrix metalloproteinase. 2009 Jun 1 1
20 19657566 TGF-beta promotes invasion and metastasis of gastric cancer cells by increasing fascin1 expression via ERK and JNK signal pathways. 2009 Aug 2
21 18192325 Transforming growth factor-beta-induced alpha-smooth muscle cell actin expression in renal proximal tubular cells is regulated by p38beta mitogen-activated protein kinase, extracellular signal-regulated protein kinase1,2 and the Smad signalling during epithelial-myofibroblast transdifferentiation. 2008 May 1
22 18346908 TGF-beta1 targets the GSK-3beta/beta-catenin pathway via ERK activation in the transition of human lung fibroblasts into myofibroblasts. 2008 Apr 2
23 17409139 MEK1/2 inhibitors block basal and transforming growth factor 1beta1-stimulated JC virus multiplication. 2007 Jun 1
24 17427197 D-glucose stimulation of L-arginine transport and nitric oxide synthesis results from activation of mitogen-activated protein kinases p42/44 and Smad2 requiring functional type II TGF-beta receptors in human umbilical vein endothelium. 2007 Sep 1
25 17457842 Flashlamp pulsed-dye laser suppressed TGF-beta1 expression and proliferation in cultured keloid fibroblasts is mediated by MAPK pathway. 2007 Apr 1
26 17467690 Epidermal growth factor and transforming growth factor-beta1 enhance HK-2 cell migration through a synergistic increase of matrix metalloproteinase and sustained activation of ERK signaling pathway. 2007 Jul 1 2
27 16361081 TGF-beta regulates differentially the proliferation of fetal and adult human skin fibroblasts via the activation of PKA and the autocrine action of FGF-2. 2006 Sep 1
28 16598650 Role of extracellular signal-regulated kinase, p38 kinase, and activator protein-1 in transforming growth factor-beta1-induced alpha smooth muscle actin expression in human fetal lung fibroblasts in vitro. 2006 Jan-Feb 2
29 16914898 Endoglin modulation of TGF-beta1-induced collagen synthesis is dependent on ERK1/2 MAPK activation. 2006 1
30 17003485 ERK, p38, and Smad signaling pathways differentially regulate transforming growth factor-beta1 autoinduction in proximal tubular epithelial cells. 2006 Oct 3
31 15468069 TGF-beta-induced expression of tissue inhibitor of metalloproteinases-3 gene in chondrocytes is mediated by extracellular signal-regulated kinase pathway and Sp1 transcription factor. 2005 May 1
32 15814533 Glucose degradation products downregulate ZO-1 expression in human peritoneal mesothelial cells: the role of VEGF. 2005 Jul 1
33 15879099 Pertussis toxin (PTX) B subunit and the nontoxic PTX mutant PT9K/129G inhibit Tat-induced TGF-beta production by NK cells and TGF-beta-mediated NK cell apoptosis. 2005 May 15 2
34 15955090 Smad3 and extracellular signal-regulated kinase 1/2 coordinately mediate transforming growth factor-beta-induced expression of connective tissue growth factor in human fibroblasts. 2005 Jun 1
35 16105451 [Transforming growth factor-beta1 induced phenotypic differentiation of human lung fibroblasts through mitogen activated protein kinase-dependent pathway]. 2005 Apr 2
36 14688282 Distinct roles of Smad2-, Smad3-, and ERK-dependent pathways in transforming growth factor-beta1 regulation of pancreatic stellate cellular functions. 2004 Mar 5 2
37 14726474 B-type natriuretic peptide exerts broad functional opposition to transforming growth factor-beta in primary human cardiac fibroblasts: fibrosis, myofibroblast conversion, proliferation, and inflammation. 2004 Mar 5 1
38 15001985 Collaborative activities of macrophage-stimulating protein and transforming growth factor-beta1 in induction of epithelial to mesenchymal transition: roles of the RON receptor tyrosine kinase. 2004 Mar 4 1
39 15095341 Involvement of ERK1/2 pathway in TGF-beta1-induced VEGF secretion in normal human cytotrophoblast cells. 2004 Jun 1
40 12457461 Early stimulation and late inhibition of peroxisome proliferator-activated receptor gamma (PPAR gamma) gene expression by transforming growth factor beta in human aortic smooth muscle cells: role of early growth-response factor-1 (Egr-1), activator protein 1 (AP1) and Smads. 2003 Mar 15 1
41 12637634 Pentoxifylline modulates intracellular signalling of TGF-beta in cultured human peritoneal mesothelial cells: implications for prevention of encapsulating peritoneal sclerosis. 2003 Apr 1
42 12760902 Regulation of IL-11 expression in intestinal myofibroblasts: role of c-Jun AP-1- and MAPK-dependent pathways. 2003 Sep 2
43 11842088 Cross-talk between ERK and p38 MAPK mediates selective suppression of pro-inflammatory cytokines by transforming growth factor-beta. 2002 Apr 26 1
44 11880276 Laminins and TGF-beta maintain cell polarity and functionality of human gastric glandular epithelium. 2002 Apr 1
45 11500937 Involvement of p38 MAP kinase in TGF-beta-stimulated VEGF synthesis in aortic smooth muscle cells. 2001 1
46 11576339 Dipyridamole inhibits TGF-beta-induced collagen gene expression in human peritoneal mesothelial cells. 2001 Oct 1
47 10708950 Role of Ras and Mapks in TGFbeta signaling. 2000 Mar-Jun 3
48 10843986 Requirement of Ras/MAPK pathway activation by transforming growth factor beta for transforming growth factor beta 1 production in a Smad-dependent pathway. 2000 Oct 6 3
49 10850453 Mitogenic conversion of transforming growth factor-beta1 effect by oncogenic Ha-Ras-induced activation of the mitogen-activated protein kinase signaling pathway in human prostate cancer. 2000 Jun 1 1
50 10862759 Transforming growth factor-beta 1-induced activation of the ERK pathway/activator protein-1 in human lung fibroblasts requires the autocrine induction of basic fibroblast growth factor. 2000 Sep 8 1