Title : Transient Receptor Potential Vanilloid channel regulates fibroblast differentiation and airway remodeling by modulating redox signals through NADPH Oxidase 4.

Pub. Date : 2020 Jun 17

PMID : 32555397






2 Functional Relationships(s)
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Protein Name
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1 NOX4-mediated ROS production is essential for TGFbeta1-induced LF differentiation via myocardin-related transcription factor-A (MRTF-A) and plasminogen activator inhibitor 1 (PAI-1). Reactive Oxygen Species transforming growth factor beta 1 Homo sapiens
2 Importantly, TRPV4 inhibition prevented TGFbeta1-induced NOX4 expression and ROS production. Reactive Oxygen Species transforming growth factor beta 1 Homo sapiens