Sulfhydryl Compounds

glutaredoxin ; Homo sapiens







67 Article(s)
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1 34541904 Thiol-Based Antioxidants and the Epithelial/Mesenchymal Transition in Cancer. 2022 May 2
2 33359085 Cellular S-denitrosylases: Potential role and interplay of Thioredoxin, TRP14, and Glutaredoxin systems in thiol-dependent protein denitrosylation. 2021 Feb 1
3 32618039 Glutaredoxin 1 Downregulation in the Substantia Nigra Leads to Dopaminergic Degeneration in Mice. 2020 Oct 2
4 30367780 Structural and mechanistic aspects of S-S bonds in the thioredoxin-like family of proteins. 2019 Apr 24 2
5 30552876 Molecular Mechanisms of Glutaredoxin Enzymes: Versatile Hubs for Thiol-Disulfide Exchange between Protein Thiols and Glutathione. 2019 Jan 18 2
6 30593501 Kinetic studies reveal a key role of a redox-active glutaredoxin in the evolution of the thiol-redox metabolism of trypanosomatid parasites. 2019 Mar 1 2
7 30639960 Thioredoxin and glutaredoxin regulate metabolism through different multiplex thiol switches. 2019 Feb 2
8 31680614 Deletion of glutaredoxin promotes oxidative tolerance and intracellular infection in Listeria monocytogenes. 2019 Dec 1
9 29261301 Redox-Inactive Peptide Disrupting Trx1-Ask1 Interaction for Selective Activation of Stress Signaling. 2018 Feb 6 2
10 29410996 Modulation of thiol-dependent redox system by metal ions via thioredoxin and glutaredoxin systems. 2018 Feb 21 2
11 30140002 Inhibition of the glutaredoxin and thioredoxin systems and ribonucleotide reductase by mutant p53-targeting compound APR-246. 2018 Aug 23 2
12 28411237 Physical interaction between human ribonucleotide reductase large subunit and thioredoxin increases colorectal cancer malignancy. 2017 Jun 2 2
13 28746987 Cytosolic redox components regulate protein homeostasis via additional localisation in the mitochondrial intermembrane space. 2017 Sep 1
14 26593282 Comparison of methods probing the intracellular redox milieu in Plasmodium falciparum. 2016 Mar-Apr 1
15 26795153 Nuclear thiol redox systems in plants. 2016 Feb 2
16 27490699 The Myeloablative Drug Busulfan Converts Cysteine to Dehydroalanine and Lanthionine in Redoxins. 2016 Aug 23 1
17 27827892 Salvianolic Acid B (Sal B) Protects Retinal Pigment Epithelial Cells from Oxidative Stress-Induced Cell Death by Activating Glutaredoxin 1 (Grx1). 2016 Nov 3 2
18 25392302 Kinetic control by limiting glutaredoxin amounts enables thiol oxidation in the reducing mitochondrial intermembrane space. 2015 Jan 15 1
19 23836328 Plasma glutaredoxin activity in healthy subjects and patients with abnormal glucose levels or overt type 2 diabetes. 2014 Apr 2
20 24863694 Protective effects of the thioredoxin and glutaredoxin systems in dopamine-induced cell death. 2014 Aug 2
21 25537203 Loss of thiol repair systems in human cataractous lenses. 2014 Dec 23 2
22 22299579 Evaluation of a dithiocarbamate derivative as an inhibitor of human glutaredoxin-1. 2013 Jun 1
23 22909029 Thioredoxin glutathione reductase-dependent redox networks in platyhelminth parasites. 2013 Sep 1 2
24 23957891 Thiol-dependent recovery of catalytic activity from oxidized protein tyrosine phosphatases. 2013 Sep 17 1
25 24025674 Transient light-induced intracellular oxidation revealed by redox biosensor. 2013 Oct 4 1
26 21954972 Mitochondrial thiols in antioxidant protection and redox signaling: distinct roles for glutathionylation and other thiol modifications. 2012 Mar 15 1
27 22247548 Five decades with glutathione and the GSTome. 2012 Feb 24 1
28 20552295 Cadmium affects the glutathione/glutaredoxin system in germinating pea seeds. 2011 Jul 1
29 21051543 Linked thioredoxin-glutathione systems in platyhelminth parasites: alternative pathways for glutathione reduction and deglutathionylation. 2011 Feb 18 2
30 21936800 Thiol regulation of pro-inflammatory cytokines and innate immunity: protein S-thiolation as a novel molecular mechanism. 2011 Oct 2
31 22139372 Vertebrate-specific glutaredoxin is essential for brain development. 2011 Dec 20 1
32 20829229 Glutaredoxin 2 prevents aggregation of mutant SOD1 in mitochondria and abolishes its toxicity. 2010 Nov 15 1
33 18321861 Inhibition of the human thioredoxin system. A molecular mechanism of mercury toxicity. 2008 May 2 2
34 18560520 Knockdown of cytosolic glutaredoxin 1 leads to loss of mitochondrial membrane potential: implication in neurodegenerative diseases. 2008 Jun 18 6
35 19216714 Involvement of thio-, peroxi-, and glutaredoxins in cellular redox-dependent processes. 2008 Dec 3
36 17115886 Thioredoxin and related molecules--from biology to health and disease. 2007 Jan 1
37 17172268 Thiol-based mechanisms of the thioredoxin and glutaredoxin systems: implications for diseases in the cardiovascular system. 2007 Mar 1
38 17514531 Revival of glutathione reductase in human cataractous and clear lens extracts by thioredoxin and thioredoxin reductase, in conjunction with alpha-crystallin or thioltransferase. 2007 May 3
39 16605247 Computational and mutational analysis of human glutaredoxin (thioltransferase): probing the molecular basis of the low pKa of cysteine 22 and its role in catalysis. 2006 Apr 18 2
40 17034357 Role of reversible, thioredoxin-sensitive oxidative protein modifications in cardiac myocytes. 2006 Nov-Dec 2
41 23045137 Measurement of protein glutathionylation. 2006 Jun 2
42 16246122 Thiol redox control via thioredoxin and glutaredoxin systems. 2005 Dec 5
43 16262253 Reaction mechanism and regulation of mammalian thioredoxin/glutathione reductase. 2005 Nov 8 1
44 15109915 Protein s-glutathionylation in retinal pigment epithelium converts heat shock protein 70 to an active chaperone. 2004 Jun 2
45 12556467 Glutathione-thiyl radical scavenging and transferase properties of human glutaredoxin (thioltransferase). Potential role in redox signal transduction. 2003 Apr 25 3
46 12565802 Reversal of protein S-glutathiolation by glutaredoxin in the retinal pigment epithelium. 2003 Feb 1
47 12745250 Endogenous oxidoreductase expression is induced by aminoglycosides. 2003 Jun 1 1
48 12804604 Essential 110Cys in active site of membrane-associated prostaglandin E synthase-2. 2003 Jun 27 1
49 12244106 Role of glutaredoxin in metabolic oxidative stress. Glutaredoxin as a sensor of oxidative stress mediated by H2O2. 2002 Nov 29 1
50 12351714 Thioltransferase (glutaredoxin) mediates recovery of motor neurons from excitotoxic mitochondrial injury. 2002 Oct 1 1