| 1 |
35454074 | In Search of Differential Inhibitors of Aldose Reductase. | 2022 Mar 22 |
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| 2 |
33109031 | Development of Aldose Reductase Inhibitors for the Treatment of Inflammatory Disorders and Cancer: Current Drug Design Strategies and Future Directions. | 2021 |
2 |
| 3 |
33494154 | Aldose Reductase and the Polyol Pathway in Schwann Cells: Old and New Problems. | 2021 Jan 21 |
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| 4 |
33776930 | Aldose Reductase: An Emerging Target for Development of Interventions for Diabetic Cardiovascular Complications. | 2021 |
2 |
| 5 |
33906691 | Rhodanine-3-acetamide derivatives as aldose and aldehyde reductase inhibitors to treat diabetic complications: synthesis, biological evaluation, molecular docking and simulation studies. | 2021 Apr 27 |
2 |
| 6 |
33945128 | Aldo Keto Reductases AKR1B1 and AKR1B10 in Cancer: Molecular Mechanisms and Signaling Networks. | 2021 |
2 |
| 7 |
34084181 | The relationship between aldose reductase gene C106T polymorphism and the severity of retinopathy in Type 2 diabetic patients: A case-control study. | 2021 |
2 |
| 8 |
34120350 | The role of thrifty genes in the origin of alcoholism: A narrative review and hypothesis. | 2021 Aug |
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| 9 |
34250604 | Aqueous extract prepared from steamed red amaranth (Amaranthus gangeticus L.) leaves protected human lens cells against high glucose induced glycative and oxidative stress. | 2021 Aug |
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| 10 |
34314916 | Development of coumarin-thiosemicarbazone hybrids as aldose reductase inhibitors: Biological assays, molecular docking, simulation studies and ADME evaluation. | 2021 Oct |
2 |
| 11 |
34677370 | Physiological and Pathological Roles of Aldose Reductase. | 2021 Sep 27 |
2 |
| 12 |
34768205 | Biological effects of bis-hydrazone compounds bearing isovanillin moiety on the aldose reductase. | 2021 Dec |
2 |
| 13 |
31589122 | Natural Aldose Reductase Inhibitor: A Potential Therapeutic Agent for Non-alcoholic Fatty Liver Disease. | 2020 |
1 |
| 14 |
31978681 | Search for non-acidic ALR2 inhibitors: Evaluation of flavones as targeted agents for the management of diabetic complications. | 2020 Mar |
1 |
| 15 |
32827651 | Glucose induces metabolic reprogramming in neutrophils during type 2 diabetes to form constitutive extracellular traps and decreased responsiveness to lipopolysaccharides. | 2020 Dec 1 |
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| 16 |
30551808 | Benzoxazinone-thiosemicarbazones as antidiabetic leads via aldose reductase inhibition: Synthesis, biological screening and molecular docking study. | 2019 Jun |
2 |
| 17 |
30818176 | Synthesis of new arylsulfonylspiroimidazolidine-2',4'-diones and study of their effect on stimulation of insulin release from MIN6 cell line, inhibition of human aldose reductase, sorbitol accumulations in various tissues and oxidative stress. | 2019 Apr 15 |
2 |
| 18 |
30986766 | Aldose reductase regulates hyperglycemia-induced HUVEC death via SIRT1/AMPK-α1/mTOR pathway. | 2019 Jul 1 |
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| 19 |
31389594 | Aldose reductase inhibitor Epalrestat alleviates high glucose-induced cardiomyocyte apoptosis via ROS. | 2019 Aug |
2 |
| 20 |
31636082 | Repurposing the aldose reductase inhibitor and diabetic neuropathy drug epalrestat for the congenital disorder of glycosylation PMM2-CDG. | 2019 Nov 11 |
2 |
| 21 |
29343522 | Polyol Pathway Links Glucose Metabolism to the Aggressiveness of Cancer Cells. | 2018 Apr 1 |
2 |
| 22 |
29371030 | Regulation on SIRT1-PGC-1α/Nrf2 pathway together with selective inhibition of aldose reductase makes compound hr5F a potential agent for the treatment of diabetic complications. | 2018 Apr |
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| 23 |
29693278 | Inhibition of C298S mutant of human aldose reductase for antidiabetic applications: Evidence from in silico elementary mode analysis of biological network model. | 2018 Aug |
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| 24 |
29705708 | Design, synthesis, structure-activity relationships and X-ray structural studies of novel 1-oxopyrimido[4,5-c]quinoline-2-acetic acid derivatives as selective and potent inhibitors of human aldose reductase. | 2018 May 25 |
4 |
| 25 |
29863179 | Redox imbalance stress in diabetes mellitus: Role of the polyol pathway. | 2018 Mar |
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| 26 |
30009780 | Regulation of aldose reductase activity by tubulin and phenolic acid derivates. | 2018 Sep 15 |
2 |
| 27 |
27208686 | Increased sorbitol levels in the hypertrophic ligamentum flavum of diabetic patients with lumbar spinal canal stenosis. | 2017 May |
3 |
| 28 |
27835059 | Epalrestat, an Aldose Reductase Inhibitor Prevents Glucose-Induced Toxicity in Human Retinal Pigment Epithelial Cells In Vitro. | 2017 Jan/Feb |
2 |
| 29 |
27894247 | Aldose Reductase as a Drug Target for Treatment of Diabetic Nephropathy: Promises and Challenges. | 2017 |
2 |
| 30 |
28159579 | Edible vegetables as a source of aldose reductase differential inhibitors. | 2017 Oct 1 |
1 |
| 31 |
28302016 | Validation of TZD Scaffold as Potential ARIs: Pharmacophore Modeling, Atom-based 3D QSAR and Docking Studies. | 2017 |
2 |
| 32 |
28501572 | Quercetin inhibited epithelial mesenchymal transition in diabetic rats, high-glucose-cultured lens, and SRA01/04 cells through transforming growth factor-β2/phosphoinositide 3-kinase/Akt pathway. | 2017 Sep 5 |
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| 33 |
30023751 | New Insights into the Catalytic Mechanism of Aldose Reductase: A QM/MM Study. | 2017 Sep 30 |
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| 34 |
26349493 | Updates on Aldose Reductase Inhibitors for Management of Diabetic Complications and Non-diabetic Diseases. | 2016 |
2 |
| 35 |
26823999 | The metabolomic profile of gamma-irradiated human hepatoma and muscle cells reveals metabolic changes consistent with the Warburg effect. | 2016 |
1 |
| 36 |
27140653 | Characterization of Emodin as a Therapeutic Agent for Diabetic Cataract. | 2016 May 27 |
2 |
| 37 |
27189166 | Circulating Neutrophil Extracellular Trap Levels in Well-Controlled Type 2 Diabetes and Pathway Involved in Their Formation Induced by High-Dose Glucose. | 2016 |
1 |
| 38 |
27190083 | Ranirestat has a stronger inhibitory activity on aldose reductase and suppresses inflammatory reactions in high glucose-exposed endothelial cells. | 2016 Jul |
1 |
| 39 |
27628063 | Osmotic expression of aldose reductase in retinal pigment epithelial cells: involvement of NFAT5. | 2016 Dec |
1 |
| 40 |
27685794 | In vitro and in vivo inhibition of aldose reductase and advanced glycation end products by phloretin, epigallocatechin 3-gallate and [6]-gingerol. | 2016 Dec |
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| 41 |
24903533 | Design, synthesis and evaluation of rhodanine derivatives as aldose reductase inhibitors. | 2015 Feb |
2 |
| 42 |
25283348 | Hyperglycemia and redox status regulate RUNX2 DNA-binding and an angiogenic phenotype in endothelial cells. | 2015 Jan |
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| 43 |
25451566 | Aldose reductase inhibition alleviates hyperglycemic effects on human retinal pigment epithelial cells. | 2015 Jun 5 |
2 |
| 44 |
25528584 | L-Idose: an attractive substrate alternative to D-glucose for measuring aldose reductase activity. | 2015 Jan 24 |
3 |
| 45 |
26163626 | Aldose Reductase Inhibitor Fidarestat as a Promising Drug Targeting Autophagy in Colorectal Carcinoma: a Pilot Study. | 2015 |
3 |
| 46 |
26215787 | Modulation of aldose reductase activity by aldose hemiacetals. | 2015 Nov |
3 |
| 47 |
24236461 | Alkaloids as aldose reductase inhibitors, with special reference to berberine. | 2014 Mar |
1 |
| 48 |
23747692 | Evaluation of the prostaglandin F synthase activity of human and bovine aldo-keto reductases: AKR1A1s complement AKR1B1s as potent PGF synthases. | 2013 Oct |
1 |
| 49 |
23770200 | Aldose reductase regulates acrolein-induced cytotoxicity in human small airway epithelial cells. | 2013 Dec |
4 |
| 50 |
23850972 | Association study of sorbitol dehydrogenase -888G>C polymorphism with type 2 diabetic retinopathy in Caucasian-Brazilians. | 2013 Oct |
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